Blood and immune: intro Flashcards
innate immune system
first and response
- not pathogen specific
- physical barriers
- non specific cells and molecules (phagocytes)
- inflammatory response and natural killer and defensive cells/proteins
- no memory
adaptive immune system
third line of defense
- pathogen specific
- lymphocytes, B + T cells
- antibodyes
plasma
no cells, lots of proteins and antibodies used n immune response
buffy coat
the small section of centrifuged blood sample that contains platelets and white blood cells
white blood cell types
neutrophils - blobbing nuclei, (adaptive and phagocytic)
lymphocytes - small, near circular nuclei (adaptive immune, b and t cells)
monocytes - kidney nuclei (innate immune)
pathology
study of diseases and hoy they progress
pathogen
agent that causes a diesease
immune sytem
a system to stop invading pathogens
immunogenic
something that induces an immune response (antibody or cell mediated immune response) (ie the virus)
antigen
a molecule or part of something that induces immune response (pathogens will have antigens on their surface, ie spike protein on a virus)
must be
- immunogenic
- reactive with antibodies
- have epitopes: the part of an antigen molecule to which an antibody attaches itself.
antibody
protein a molecular component of the immune system hat recognises and binds/interacts with antigens
how pathogens enter
breath
eat
touch
blocked by skin, secreations mucos membranes (innate barriers)
first steps in innate response from cutting
- tissue cells damaged
- cells release chemicals like histamine
- histamine makes nearby blood cells leaky and fluid release causes swelling
- factors in fluid heal and clot
- phagocytes activated