Blood and immune: intro Flashcards

1
Q

innate immune system

A

first and response
- not pathogen specific
- physical barriers
- non specific cells and molecules (phagocytes)
- inflammatory response and natural killer and defensive cells/proteins
- no memory

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2
Q

adaptive immune system

A

third line of defense
- pathogen specific
- lymphocytes, B + T cells
- antibodyes

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3
Q

plasma

A

no cells, lots of proteins and antibodies used n immune response

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4
Q

buffy coat

A

the small section of centrifuged blood sample that contains platelets and white blood cells

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5
Q

white blood cell types

A

neutrophils - blobbing nuclei, (adaptive and phagocytic)
lymphocytes - small, near circular nuclei (adaptive immune, b and t cells)
monocytes - kidney nuclei (innate immune)

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6
Q

pathology

A

study of diseases and hoy they progress

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7
Q

pathogen

A

agent that causes a diesease

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8
Q

immune sytem

A

a system to stop invading pathogens

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9
Q

immunogenic

A

something that induces an immune response (antibody or cell mediated immune response) (ie the virus)

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10
Q

antigen

A

a molecule or part of something that induces immune response (pathogens will have antigens on their surface, ie spike protein on a virus)
must be
- immunogenic
- reactive with antibodies
- have epitopes: the part of an antigen molecule to which an antibody attaches itself.

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11
Q

antibody

A

protein a molecular component of the immune system hat recognises and binds/interacts with antigens

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12
Q

how pathogens enter

A

breath
eat
touch
blocked by skin, secreations mucos membranes (innate barriers)

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13
Q

first steps in innate response from cutting

A
  • tissue cells damaged
  • cells release chemicals like histamine
  • histamine makes nearby blood cells leaky and fluid release causes swelling
  • factors in fluid heal and clot
  • phagocytes activated
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