muscle: intro and skeletal muscle 1 Flashcards
types of muscle
skeletal muscle
cardiac muscle
structure of skeletal muscle
striated
single long cylindrical cells
multiple peripheral nuclei
attatched to bones via tendons
- made of myofibrils with the contractile unit, the sarcomere
cardiac muscle
only in heart
striated
branched with 1-3 central nuclei
connected via intercalated discs
involuntary control
smooth muscle
involuntary control
found in wall of internal organs
spindle shaped, uninucleated
not striated
role of calcium
calcium binds with troponin and the tropomysosin moves the mysosin binding sites on actin
cross bridge cycle continues so long as calcium levels remain above critical threshold (o.001-0.01mM)
sliding filament theory
sarcomere shorten as thin filaments are pulled over thick filaments
z line is pulled toward m line
t band and h zone become narrower
isotonic
shortening
tension constant
velocity variable
isometric
no shortening
length constant
tension variable
calciu regulation
- in skeletal muscle, Ca channels open in SR and calcium ions are able to move into cytosol
- active transport Ca ATPase constantly moving calcium from cytoplasm back to SR