Blood and immune: antibodies and gene reaarangement

Question 1

affinity

Answer 1

total sum of attractive forces that exceeds the repulsive forces - a measure of how tightly two molecules bind and how quickly they find each other and how long it takes them to dissociate

Question 2

avidity

Answer 2

multiple affinity contacts - important function in the activation of adaptive immune repsonse

Question 3

antibody classes

Answer 3

IgM - serum and membrane, default (every b cell makes in bone marrow)
IgG - serum, most common
IgE - serum
IgA - serum and mucosa

Question 4

effector functions

Answer 4

IgM - forms pentamer, first line of interaction with invading microbes, low affinity, high avidity
IgG -

Question 5

immunoglobulin protein fold

Answer 5

antibodies are made of repeating protein units called Ig domains that is two anti-parallel beta pleated sheets joined int he middle by a disulphide bond

Question 6

adaptive immunity origins

Answer 6

transposon codes

Question 7

complemtarity

Answer 7

the similarity between two surfaces, great amount of affinity