Blood and immune: blood composition Flashcards
blood components
- cells - erythroid, myeloid, lymphoid
- proteins - albumin, haemoglobin, fibrinogen, immunoglobins
- lipids - bound in lipoproteins HDL, LDL, VLDL
- electrolytes - salts and minerals
- vitamines hormones
- glucose
blood cells
erythrocytes - oxygen transport
leukocytes - immune defense
platelets - coagulation and tissue repair
blood circulation
right = blood to lungs to heat
left = heart to body
left ventricle does the pumping
large vessels = high volume low flow
small vessels low volume high flow
blood proteins
plasma - has fibrinogen
serum. - fibrinogen removed during coagulation
serum proteins will separate into 5 distinct bands when exosed to an electric field
1. albumin - 50%
2. globulin - 40%
also haemoglobin, made of four heme groups that bind to oxygen
albumin
maintains osmotic pressure
bidns and transportes many small molecules
fibrinogen
activated through coagulation cascade to form cross-linked fibrin
haematopoiesis
propogation of white blood cells
complement cascade
a series of proteins that undergo activation and sequential steps for innate immunity
white blood cells
monocytes - becomes macrophages
eosinophil - granulated
basophil - granulated
lymphocytes - b cells and t cells -immunity
neutrophils - phagocytic - 3 lobed nucleus, they can move
serum vs plasma
serum is just plasma that has been coagulated and allowed to clot. plasma still has fibrinogen that would get removed during coagulation