Blood and immune: blood composition Flashcards

1
Q

blood components

A
  1. cells - erythroid, myeloid, lymphoid
  2. proteins - albumin, haemoglobin, fibrinogen, immunoglobins
  3. lipids - bound in lipoproteins HDL, LDL, VLDL
  4. electrolytes - salts and minerals
  5. vitamines hormones
  6. glucose
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2
Q

blood cells

A

erythrocytes - oxygen transport
leukocytes - immune defense
platelets - coagulation and tissue repair

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3
Q

blood circulation

A

right = blood to lungs to heat
left = heart to body
left ventricle does the pumping
large vessels = high volume low flow
small vessels low volume high flow

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4
Q

blood proteins

A

plasma - has fibrinogen
serum. - fibrinogen removed during coagulation
serum proteins will separate into 5 distinct bands when exosed to an electric field
1. albumin - 50%
2. globulin - 40%
also haemoglobin, made of four heme groups that bind to oxygen

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5
Q

albumin

A

maintains osmotic pressure
bidns and transportes many small molecules

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6
Q

fibrinogen

A

activated through coagulation cascade to form cross-linked fibrin

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7
Q

haematopoiesis

A

propogation of white blood cells

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7
Q

complement cascade

A

a series of proteins that undergo activation and sequential steps for innate immunity

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7
Q

white blood cells

A

monocytes - becomes macrophages
eosinophil - granulated
basophil - granulated
lymphocytes - b cells and t cells -immunity
neutrophils - phagocytic - 3 lobed nucleus, they can move

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8
Q

serum vs plasma

A

serum is just plasma that has been coagulated and allowed to clot. plasma still has fibrinogen that would get removed during coagulation

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