Muscle Physiology 1-2 Flashcards

1
Q

What are the 4 specific properties of muscle

A
  1. Contractility
  2. Excitability
  3. Extensibility
  4. Elasticity
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2
Q

The ability to contract or shorten

A

Contractility

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3
Q

the capacity to receive and respond to stimulus

A

excitability

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4
Q

the ability to be streched

A

Extensibility

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5
Q

The ability to return to original shape after being streched

A

Elasticity

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6
Q

What are the 3 types of muscle

A
  1. Skeletal
  2. Smooth
  3. Cardiac
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7
Q

List the levels of organization of skeletal muscle from outside in.

A
  1. Epimysium
  2. Fascicle
  3. Perimysium
  4. Endomysium
  5. sarcolema
  6. Muscle fibers
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8
Q

What are the 2 types of muscle fibers?

A
  1. Red/Type I/ Slow twich

2. White/ Type II/ Fast twitch

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9
Q

The basic contractile unit of striated muscle fibers

A

Sarcomeres

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10
Q

What are the 2 types of myofilaments?

A
  1. Actin (thin)

2. Myosin (thick)

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11
Q

Specialized ER found in muscle cells

A

Sarcoplasmic reticulum (SR)

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12
Q

What is the function of SR?

A

Regulate Calcium storage, release, and reuptake

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13
Q

T/F. the SR is bigger in Red muscle

A

F. Larger in White muscle

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14
Q

T/F. Red muscle has more mitochondria than white.

A

T

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15
Q

Allow the PM of the muscle fiber to carry the depolarization of the AP to the interior of the fiber

A

T-Tubules

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16
Q

Junction between a nerve fiber and muscle cell

A

Neuromuscular junction

17
Q

The diffusion potential level across a memb. that exactly opposes the net diffusion of a particular ion through the memb.

A

Nerst potential

18
Q

What are the 3 forces that cause diffusion of molecules and ions through a CM?

A
  1. Net diffusion rate
  2. Nerst Potential
  3. Pressure diff.
19
Q

What is the resting potential fo nerve fibers when not transmitting signals?

A

-70mV

20
Q

What are the 3 factors that determine resting potential?

A
  1. diffusion of K through the nerve cell memb.
  2. diffusion of Na through the nerve cell memb.
  3. Contribution of the Na/K pump
21
Q

What allows K to diffuse out of the cell?

A

K leak channels

22
Q

What allows Na to diffuse out of cell?

A

Na leak channels

23
Q

T/F. the memb. is far less permeable to Na than K.

A

T

24
Q

What is the most important contributor to resting potential?

A

K diffusion

25
Q

How many ions of sodium and potassium does the Na/K pump pump in and out of the cell?

A

2K ions in

3Na ions out

26
Q

how are nerve signals transmitted?

A

AP

27
Q

Rapid changes in the memb. potential that spread rapidly along the nerve fiber memb.

A

AP

28
Q

What are the 3 stages of an AP?

A
  1. Resting
  2. depolarizing
  3. repolarizing
29
Q

Moment before AP begins

A

Resting stage

30
Q

Stage of AP where a threshold for the initiation of the AP has been achieved.

A

Depolarization state

31
Q

During depolarization is the memb. potential rising in the positive or negative direction?

A

positive

32
Q

How does the massive Na influx occur?

A

Voltage-Gated sodium channels

33
Q

Stage of AP after the memb. becomes highly permeable to Na ions, and the Na channels begin to close

A

Repolarization

34
Q

What channels open during the repolarization stage?

A

voltage gated K channels

35
Q

Re-establishment of the normal negative resting potential

A

Repolarization

36
Q

What is the Refractory period?

A

A new AP cannot occur in an excitable fiber as long as the memb. is still depolarized from the preceding AP

37
Q

the period during which an second AP cannot be elicited

A

Absolute Refractory Period