Muscle Contraction Flashcards
what proteins interact to cause muscles to contract?
actin & myosin using ATP as source
whats phase 1 of muscular contraction?
for contraction to occur, part of the myosin molecule (head group) attaches to a binding site on the actin filament - cross bridge = formed.
whats phase 2 of muscular contraction?
the head group bends, pulling the actin filament along & ADP and P are released - power stroke.
whats phase 3 of muscle contraction?
the attachment of a new ATP molecule to the myosin head breaks the cross bridge
whats phase 4 of muscular contraction?
the head group moves back to its original confirmation as ATP is hydrolysed to ADP & P so another cross bridge can be formed.
what is myosin?
thick protein filament, each molecule consisting of a tail & two head regions.
what is actin?
thin filament of globular subunits, twisted like a double strand of beads.
how do muscle cells produce a force on contraction?
they contain filaments made of actin & myosin,
whats ATP role in muscle contraction?
ATP = unstable but only small amounts of it exist in cells at any one time. contraction uses a lot of ATP which is completely used up after 2 secs.