Muscle 2 Flashcards
a motor neuron and all of the muscle fibers it innervates
motor unit
specialized domain of the sarcolemma
highly excitable
responsible for initiating the AP that propagates across the myofibers causing muscle contraction
motor end plate
junction of the axon terminal of a motor neuron with a motor end plate
specialized area of the sarcolemma of the skeletal myofiber to be innervated
neuromuscular junction
genetic diseases
caused by mutations in the dystrophin gene located in the X chromosome
wasting of muscles/mental retardation
muscular dystrophies
link between acting cytoskeleton and basal lamina caused by…
no dystrophin
found only in heart where it forms thick layer called myocardium
involuntary muscle
short/branched striated fibers
one central nucleus
cardiac muscle
junctional complexes found b/t 2 adjacent cardiac fibers
step-like pattern
interclated discs
runs across the fibers @ right angles
zonula adherens - anchor
desmosomes - bind fibers together
transparent part
runs parallel to the myofilaments
gap junctions - rapid flow of info b/t fibers
lateral part
involuntary non-straited fibers one central nucleus per fiber no T-tubules fibers communicate via gap junctions
smooth muscle
tunica media made up of smooth muscle cells and elastic tissues
smooth muscles control vessel diameter
smooth muscle of arteries and veins
longitudinal layer:muscle fibers run parallel to the long axis of the organ
circular layer: muscle fibers run around the circumferences of the organ
smooth muscle of intestine
consist of myosin/actin filaments attached to dense bodies in the sarcoplasm or plasma membrane
contractile units
arranged obliquely in cell
some attach to dense bodies in the cytoplasm
other attache to dense plaques of the plasma membrane
thin filaments