GI 3 - Liver, Pancreas, Gall Bladder Flashcards
Pancreas - clusters of endocrine cells without ducts
highly vascularized with many capillaries
chromophilic secretory cells
endocrine islets
secrete glucagon; increase blood glucose
a cells
secrete insulin, decrease blood glucose
beta cells
secreting apically to ducts
larger interlobular and main ducts
exocrine acini
stain with eosin apically –> chromophilic
secrete digestive enzyme in inactive form
acinar cells = zymogenic cells
secreted by DNES cells in SI and by AC released by post synapse parasympathetic nerves
enterokinase
chromophobic; many TJs between cells
secrete bicarb, Cl-, water to flush zygomes to Oddi
centroacinar + ductal cells
bile production
plamsa protein production
alcohol dehydrase
glycogen production
Liver
increase in nutrients, drains GI tract, enters liver
hepatic portal vein
high in O2
hepatic artery
drain liver of exocrine product
Bile Duct
highly synthetic(RER);highly metabolized (mitochondria) with very high storage capacity
hepatocytes
domains of hepatocytes - nutrient uptake + endocrine release to venous sinusoids
basal
domains of hepatocytes - exocrine release into bile duct
apical
venous sinusoids are patrolled by…
Kauffer cells