Cell Adhesion

Question 1

span the cell membrane + connect the inside/outside of the cell

Answer 1

transmembrane adhesion pathways

Question 2

allow recruitment of additional components to adhesion complex

Answer 2

adaptor proteins

Question 3

physical link b/t adhesion complex and cytoskeleton

Answer 3

cytoskeletal linkers

Question 4

encircle the apical end of each epithelial cell

formed from strands of interacting transmembrane proteins

Answer 4

tight junctions/zonula occuludens

Question 5

4 pass transmembrane protein

essential for TJ formation

Answer 5

Claudin

Question 6

4 pass transmembrane protein
required for barrier function
controls solute diffusion b/t our bodies components

Answer 6

Occulin

Question 7

form strong continous adhesion belts
critical in the formation of 2-D sheets of cells
composed of cadherins
link actin cytoskeleton

Answer 7

adherens junctions/zonula adherens

Question 8

bind to the keratin family of IF’s
critical for strengthening tissues
found in tissues exposed to tensile forces

Answer 8

desmosomes

Question 9

function in allowing cells to communicate and share nutrients

Answer 9

gap junctions

Question 10

gap junction adhesion proteins
6 = connexon
come together and form a functional channel b/t 2 neighbouring cells that can be regulated

Answer 10

connexins