Cartilage

Question 1

supports soft tissues
provides a low friction sliding area for joints
promotes growth of long bones as a reserve of new bone deposition @ growth plates of endochronal bone

Answer 1

functions of cartilage

Question 2

chrondoblasts start to deposit cartilage ECM in outer portion of tissue
“chondroprogenitor” cells located in outermost CT layer
chondrocytes terminally differentiated from chondroblasts and are embedded in lacunae

Answer 2

cells in cartilage

Question 3

avascular
intermediate thickness, type II collagen, provides tensile strength
resists compression

Answer 3

matrix of cartilage

Question 4

type II collagen fibers predominate
60-70% water, recruited by significant amounts of PG’s
found in joints, nose, trachea

Answer 4

hyaline cartilage

Question 5

matrix contains high amounts of thick, strong type I collagen
very, very low regenerative potential
found in intervertebral disks, pubic symphysis, sites of bone attachment

Answer 5

fibrocartilage

Question 6

decreased matrix/increased # of cells compared to hyaline cartilage
Type II collagen + elastic fiber in matrix
found in flexible areas

Answer 6

elastic cartilage

Question 7

loss of articular hyaline cartilage, can’t be regenerated as cartilage leads to bone coming in contact with bone

Answer 7

osteoarthritis