Hematopoiesis

Question 1

can self-renew

multipotent as it can give rise to all cells of the blood and megakaryocytes

Answer 1

Hematopoietic Stem Cell

Question 2

Granulocytes/Erythrocytes/Monocytes/Megakaryocytes = GEMM

Answer 2

Myeloid lineage progenitors

Question 3

B and T lymphocytes and natural killer cells

Answer 3

Lymphoid lineage progenitors

Question 4

regions in b marrow that contain HSC, lineage progenitors, blasts, supportive stromal cells where blood cell production takes place
located close to venous sinusoids which allows cells to enter and leave b marrow quickly

Answer 4

Hematopoietic Cords

Question 5

made up of clusters of developing blood cells, stromal cells, paracrine and endocrine factors as well as ECM

Answer 5

Hematopoietic Niches

Question 6

by growth factors, cytokines, colony stimulating factors produced by stromal cells in b marrow, (Stem Cell Factor)
by hormones produced in another organ (EPO)

Answer 6

Regulation of Hematopoiesis