multiple pregnancies Flashcards

1
Q

what is multiple pregnancies ?

A

when more than none embryo implants in the uterus

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2
Q

what is a heterozygotic pregnancy ?

A

more than one ovum is released during the menstrual cycle and each ovum is fertilized by a sperm

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3
Q

what is a monozygotic pregnancy ?

A

the spontaneous splitting of a single fertilized ovum resulting into identical embryos

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4
Q

what are some of the factors that increase the risk of having multiple pregnancies ?

A
  1. ovulating-stimulating medications such as clomiphene citrate
  2. assisted reproductive techniques
  3. old age
  4. high parity
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5
Q

when splitting happens of the ovum happens within two days of fertilization what type of pregnancy occurs ?

A

monozygotic pregnancy , resulting in a di-amniotic and di-chorionic pregnancy

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6
Q

when splitting of the ovum happens after 3-8 days after fertilization what type pf pregnancy occurs ?

A

monochorionic and diamniotic

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7
Q

what type of pregnancy occurs if splitting happens at 9-12 after fertilization ?

A

monochorionic

monoamniotic placentation

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8
Q

what happens is splitting of the ovum happens more than n12 days after fertilization n?

A

results in conjoined twins

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9
Q

how do we make a clinical diagnosis of multiple fetal pregnancies ?

A

by inspection: abdominal girth is larger than expected
by palpation: multiple fetal poles and limbs can be felt
by auscultation of the FHS : multiple FHS can be heard

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10
Q

what is the most reliable examination for the detection of multiple fetal pregnancies ?

A

ultrasound

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11
Q

when should routine antenatal care be performed for women with multiple pregnancies ?

A

a FCBC should be performed at 20 to 24 weeks and then repeated again nat 28 weeks

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12
Q

what can we classify the complications of multiple pregnancies to fall under ?

A

maternal complications
fetal complications
placental complications
delivery complications

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13
Q

what are the fetal complications that may occur due to multiple pregnancies ?

A
preterm birth 
birth defects 
intrauterine growth restriction and stillbirth 
spontaneous abortion
vanishing twin syndrome
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14
Q

what is the optimum time to make a diagnosis of multiple pregnancies ?

A

1st trimester or early second trimester

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15
Q

what is the management in the case of vanishing twin syndrome ?

A

no treatment necessary

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16
Q

what are the maternal complications associated with multiple pregnancies ?

A
increased risk of :
hyperemesis gravidarum 
ironn ndeficiency anemia 
gestational diabetes 
pre-eclampsia 
pregnancy induced hypertensionn 
maternal anemia 
VTE
17
Q

what problems occur with the placenta during multiple pregnancies ?

A

the placenta ages early , so not enough nutrition reaches each fetus

18
Q

what is one of the most common complications of monochorionic multiple pregnancies ?

A

feto-fetal transfusion syndrome

19
Q

what is feto-fetal transfusion syndrome ?

A

occurs when blood moves from one baby to another, which is also called twin to twin transfusion

20
Q

what is twin anemia polycythemia ?

A

it is a rare and chronic form of feto-fetal transfusion , caused by the joining of the blood vessels connecting the fetal circulation on the placenta

21
Q

what are the consequences of twin anemia polycythemia ?

A

one baby is anemic whilst the other baby suffers from polycythemia

22
Q

what is TRAP syndrome ?

A

twin reversed arterial perfusion syndrome , this is a more severe form of twin to twin transfusion

23
Q

what is the pathology in TRAP syndrome ?

A

artery to artery anastomosis between the umbilical arteries of both twins ( one heart two babies)

24
Q

what is the most common complication associated with mono-amniotic pregnancies ?

A

cord entanglement

25
Q

how do we treat twin to twin transfusion syndrome ?

A

intrauterine laser ablation of placental vessels , vessels that are found to communicate between the twins are then coagulated using the laser

26
Q

what are the delivery complications associated with multiple pregnancies ?

A

postpartum haemorrhage
locked twins
abnormal fetal positioning raises the chances for the performance of a c section

27
Q

what is locked twins ?

A

twin a is in a cephalic position

twin b is in a breech position

28
Q

when do we offer planned birth ?

A
  1. uncomplicated dichorionic diamniotic at 37 weeks
  2. uncomplicated monochorionic diamniotic at 36 weeks
  3. uncomplicated monochorionic monoamniotic at 32-34 weeks
29
Q

when can we offer a vaginal delivery ?

A

if the first twin is cephalic presentation
no significant size discordance between twins
no obstetric contraindications

30
Q

when should we offer caesarian section?

A

monochorionic monoamniotic pregnancy