high risk pregnancy - diabetes Flashcards

1
Q

what are the two types of diabetes in obstreitics ?

A

gestational DM

Pre existing DM

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2
Q

why is pregnancy diabetogenic ?

A
  1. due to the increased production of placental lactogen and placental insulinase
  2. due to increased insulin requirements
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3
Q

what are the risk factors for developing gestational diabetes ?

A

BMI above 30 Kg/m2
previous macrocosmic baby
previous gestational diabetes
family history of diabetes

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4
Q

what method is used in the diagnosis of gestational DM ?

A

2 hour 75 g oral glucose tolerance test

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5
Q

if the patient appears to be normal in her first OGTT test when should the test be repeated again ?

A

at 24-28 weeks

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6
Q

how is a diagnosis of GDM made ?

A

either :
1. a fasting plasma glucose of 100 mg or above
2 a 2 hour plasma glucose level of 140 mg or above

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7
Q

what are the maternal effects of diabetes during pregnancy ?

A

pregnancy induced hypertension
infections
obstructed labor due to a large sized baby
deficient lactation

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8
Q

what are the fetal effects of diabetes during pregnancy ?

A
abortions 
polyhydraminos 
congenital anomalies 
macrosomia 
preterm labour 
intra uterine fetal death 
neonatal mortality and morbidity
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9
Q

what is the congenital anomaly specific to gestational diabetes ?

A

sacral dysgenesis

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10
Q

why does preterm labour mainly happen ?

A

due to polyhydraminos

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11
Q

what are the common causes of intra uterine death in diabetic women?

A
ketosis 
hypoglycaemia 
pre eclampsia 
congenital anomalies 
placental insufficiency
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12
Q

how can hypoglycaemia cause intra uterine death in a diabetic pregnant woman ?

A

due to over treatment by medications

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13
Q

what are the most common causes of neonatal mortality and morbidity ?

A
hypoglycaemia 
respiratory distress syndrome 
congenital anomalies 
birth trauma 
hyperbilirubinemia
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14
Q

what advice would you give a pregnant women with diabetes ?

A

measure random blood glucose regular and follow up
exercise for about 30 mins everyday
change in diet

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15
Q

what must you do inn terms of referral when dealing with a pregnant diabetic woman ?

A

refer to both a dietician and an endocrinologist

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16
Q

what is the first line of management for a pregnant woman who has a blood glucose off 126 mg/dl or below?

A

trial of change in diet and exersice

17
Q

if blood glucose targets are not met after change inn diet and exercise what is the next best step in management ?

A

add metformin if levels are not met within 1-2 weeks

18
Q

if metformin is contraindicated or not well tolerated by the patient what is the best next step in management ?

A

add insulin

19
Q

if the blood glucose level is above 126 mg/dl what is the next best step in management ?

A

add insulin with or without metformin

20
Q

if metformin does not help meet the glucose target and insulinn is declined what should the patient take ?

A

glibenclamide

21
Q

what advise would u give for a diabetic pregnant women being treated with insulin ?

A

to always have a fast acting form of glucose due to risk of hypoglycaemia with insulin

22
Q

if insulin fails to maintain proper blood glucose what is the best next step in a management ?

A

continuous subcutaneous insulin infusion

23
Q

when should pregnant women do an ultrasound to detect fetal structural abnormalities including fetal heart abnormalities ?>

A

week 20

24
Q

how often should fetal growth and amniotic fluid volume be checked ?

A

every 4 weeks from 28 to 36 weeks

25
Q

when should routine fetal wellbeing be checked in diabetic pregnant women ?

A

at 38 weeks

26
Q

what method of tocolysis is contraindicated in pregnant women with diabetes?

A

using betamimetics

27
Q

when should a woman with pre existing DM give birth ?

A

from 37+0 weeks to

38+6 weeks

28
Q

when should a woman with GDM give birth ?

A

40 weeks + 6 days ( maximum length)

29
Q

at what range should blood glucose be kept in a pregnant woman during labour ?

A

between 72 and 126 mg/dl

30
Q

if the blood glucose levels are not maintained during labour what should be done ?

A

intravenous dextrose should be given along with insulin infusion

31
Q

what postnatal care advice should women with pre existing DM take ?

A

if they are treated with insulin to reduce their insulin dose immediatley after birth
if she is on metformin, to continue her metformin

32
Q

what advice to give pre existing DM women after labour?

A

to avoid oral hypoglycemics during breast feeding but can continue immediately after birth

33
Q

if a woman comes into the gynaecology clinic complaining of chest pain what is the first best thing to perform ?

A

an ECG

34
Q

what is the most common cause of valvular heart disease in egypt ?

A

rheumatic heart disease

35
Q

what is the most common valvular heart lesion ?

A

mitral valve lesions

36
Q

what is a key factor in most cases of aortic dissection ?

A

systolic hypertension

37
Q

what is the most common serious complication of Marfan’s syndrome ?

A

aortic dissectio n

38
Q

what is the gold standard for the diagnosis of aortic dissection ?

A

CT

39
Q

if a woman has T1DM what should be given on the onset of labour ?

A

intravenous dextrose and insulin infusion