high risk pregnancy - diabetes Flashcards

1
Q

what are the two types of diabetes in obstreitics ?

A

gestational DM

Pre existing DM

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2
Q

why is pregnancy diabetogenic ?

A
  1. due to the increased production of placental lactogen and placental insulinase
  2. due to increased insulin requirements
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3
Q

what are the risk factors for developing gestational diabetes ?

A

BMI above 30 Kg/m2
previous macrocosmic baby
previous gestational diabetes
family history of diabetes

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4
Q

what method is used in the diagnosis of gestational DM ?

A

2 hour 75 g oral glucose tolerance test

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5
Q

if the patient appears to be normal in her first OGTT test when should the test be repeated again ?

A

at 24-28 weeks

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6
Q

how is a diagnosis of GDM made ?

A

either :
1. a fasting plasma glucose of 100 mg or above
2 a 2 hour plasma glucose level of 140 mg or above

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7
Q

what are the maternal effects of diabetes during pregnancy ?

A

pregnancy induced hypertension
infections
obstructed labor due to a large sized baby
deficient lactation

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8
Q

what are the fetal effects of diabetes during pregnancy ?

A
abortions 
polyhydraminos 
congenital anomalies 
macrosomia 
preterm labour 
intra uterine fetal death 
neonatal mortality and morbidity
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9
Q

what is the congenital anomaly specific to gestational diabetes ?

A

sacral dysgenesis

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10
Q

why does preterm labour mainly happen ?

A

due to polyhydraminos

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11
Q

what are the common causes of intra uterine death in diabetic women?

A
ketosis 
hypoglycaemia 
pre eclampsia 
congenital anomalies 
placental insufficiency
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12
Q

how can hypoglycaemia cause intra uterine death in a diabetic pregnant woman ?

A

due to over treatment by medications

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13
Q

what are the most common causes of neonatal mortality and morbidity ?

A
hypoglycaemia 
respiratory distress syndrome 
congenital anomalies 
birth trauma 
hyperbilirubinemia
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14
Q

what advice would you give a pregnant women with diabetes ?

A

measure random blood glucose regular and follow up
exercise for about 30 mins everyday
change in diet

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15
Q

what must you do inn terms of referral when dealing with a pregnant diabetic woman ?

A

refer to both a dietician and an endocrinologist

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16
Q

what is the first line of management for a pregnant woman who has a blood glucose off 126 mg/dl or below?

A

trial of change in diet and exersice

17
Q

if blood glucose targets are not met after change inn diet and exercise what is the next best step in management ?

A

add metformin if levels are not met within 1-2 weeks

18
Q

if metformin is contraindicated or not well tolerated by the patient what is the best next step in management ?

A

add insulin

19
Q

if the blood glucose level is above 126 mg/dl what is the next best step in management ?

A

add insulin with or without metformin

20
Q

if metformin does not help meet the glucose target and insulinn is declined what should the patient take ?

A

glibenclamide

21
Q

what advise would u give for a diabetic pregnant women being treated with insulin ?

A

to always have a fast acting form of glucose due to risk of hypoglycaemia with insulin

22
Q

if insulin fails to maintain proper blood glucose what is the best next step in a management ?

A

continuous subcutaneous insulin infusion

23
Q

when should pregnant women do an ultrasound to detect fetal structural abnormalities including fetal heart abnormalities ?>

24
Q

how often should fetal growth and amniotic fluid volume be checked ?

A

every 4 weeks from 28 to 36 weeks

25
when should routine fetal wellbeing be checked in diabetic pregnant women ?
at 38 weeks
26
what method of tocolysis is contraindicated in pregnant women with diabetes?
using betamimetics
27
when should a woman with pre existing DM give birth ?
from 37+0 weeks to | 38+6 weeks
28
when should a woman with GDM give birth ?
40 weeks + 6 days ( maximum length)
29
at what range should blood glucose be kept in a pregnant woman during labour ?
between 72 and 126 mg/dl
30
if the blood glucose levels are not maintained during labour what should be done ?
intravenous dextrose should be given along with insulin infusion
31
what postnatal care advice should women with pre existing DM take ?
if they are treated with insulin to reduce their insulin dose immediatley after birth if she is on metformin, to continue her metformin
32
what advice to give pre existing DM women after labour?
to avoid oral hypoglycemics during breast feeding but can continue immediately after birth
33
if a woman comes into the gynaecology clinic complaining of chest pain what is the first best thing to perform ?
an ECG
34
what is the most common cause of valvular heart disease in egypt ?
rheumatic heart disease
35
what is the most common valvular heart lesion ?
mitral valve lesions
36
what is a key factor in most cases of aortic dissection ?
systolic hypertension
37
what is the most common serious complication of Marfan's syndrome ?
aortic dissectio n
38
what is the gold standard for the diagnosis of aortic dissection ?
CT
39
if a woman has T1DM what should be given on the onset of labour ?
intravenous dextrose and insulin infusion