Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

uworld > msk1 > Flashcards

msk1 Flashcards

1
Q

3rd pharyngeal pouch

A

inferir parathyroids

thymus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

immune defiency associwthe w infectioun following live vaccines

A

deficiences of T cell mediated immunity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Graft vs host disease organs

A

liver , skin , GI tract

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

gvhd

A

graft T cell sensitizioatn against host MHC antigens

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Lambert eaton myasthenic syndrome most often involves the

A

legs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

neuropsych disturbances in which muscle disroder

A

fibromyaliga

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

soft tissue tendrenss in

A

fibromyalgia

NOT POLYMYALGIA rheuamtica

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

fat cell in a fibrous capsule

A

lipomas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

clonal proliferation of benign melanocytes

A

congenital melanocytic nevi

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

failure of involution of mammary ridge

A

accessory nipple

hyperpigmentation, raised; epidermal thickening

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

hypergranulosis seen in

A

lichen planus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

thickening of spinosum

A

acanthosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

thickening of stratum spinosum and stratum corneum produce what type of plaques

A

raised scaly plaques

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

deep brachial artery

A

radial nerve (foreram extensors)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

medain nerve damage affects what artery

A

brachial artery

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

pain popping on external rotation mcmurray test

A

medial meniscal tear

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

excessive medail space widening of tibia; given a valgus force

A

MCL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

excessive prodcution of mineralized bone

A

osteosarc`oma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

frontal bossing seen in

A

achrondoplasia
and
rickets
however ricktes have decreased muscle tone causing lateral femoral and tibial bowing (genu varum)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

foreign body causes what type of inlammation

A

granulomatous inflammation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

triad of fibrous dysplasia (multiple osteolytic appearing lesions of hip and pelvis), endocrine abnormalities, and irregular cafe au lait spots suggests diagnosis of

A

McCune Albright syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

mccune albright syndrome: mutation causing

A

constitutive activatio nof G protein/Camp/adneylase cyclase causing gain of fucntion: Gs activity in mealoncytes : causing Cafe au lait macules (large, unilateral irregular border

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

endocrine abnormalities in mccune albright

A

precocious puberty, thyrotoxics, acromegaly

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

cafe au lait macules are what shaped

A

smaller, bilateral and smooth border

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

definition of heteroplasmy

A

different mitochondrial genomes within a single cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

what type of cells are langerhans cells

A

dendritic cells

derived from myeloid line

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

color of cavernous hemangiomas

A

soft blue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

in contrast to bony enlargmeent in OA, involved joints in RA have

A

active synovitis, w warmth and spongy swelling

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

sitting up from supine position involes what muscles

A

external abdominal obliques, rectus abdominis, hip flexors (psoas)

rectus femoris, sartorius, tensor fascial lata, flex as well

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

fever, pruiritic skin rash, arthalgia 7-14 days after exposure to antigen

A

serum sickness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

fibrinoid necoriss with neturophil infiltration

A

serum sickness (type III HSR - immune complex deposiotn)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

acute serum sickness is what type of hsr

A

type 3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

drug induced hyperesntiivity

A

type 3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

charactersitic finding of type 3 hypersenstiviey seru m sickness

A

Low serum C3 and C4 levels

35
Q

college quarterback: blow to arm whe ntackled mid throw

A

blow when externally rotated, abducted
anterior dislocation of humerus
flatting deltoid, protrusion of prominence

36
Q

disseminated herpes simplex infection seen in

A

immunocompromised patietns

37
Q

erythema multiforme is what type of process

A

cell mediated, Cd8+ lymphocytes

38
Q

superior displacement of medial fragment of clavicle

A

SCM

39
Q

inferior displacment of lateral fragment of clavicle

A

weight of arm and pec major

40
Q

how do glucocorticoids cause osteoporsisi

A 
decrease GI absorption of calcium, inhibit collagen syntehsis b y osteoblstst
decrease gnrh (leading to hypogoandsim< and increase urinary calcium loss
41
Q

GH deficeincy affects which bones

A

long and flat bones

unlike just long bones in achrondoplasia which also has midface hypoplsaia, macrocepahly

42
Q

exaggerated INHIBITION of chrondocyte proliferation

A

FGFR3

43
Q

which melanoma is associated with multinucleated giant melanocytes

A

lentigo maligna melanoma

44
Q

mutation in gene responsible for myelin syntehssi in child

A

charco marie tooth disease

45
Q

follwoing drug hypersentivity;

urticaria: raised erytehmatous plaques wheals caused by ig3 mediated degrnaulation of mast cells

A

urticaria

46
Q

edema of superficial dermis

A

urticaria

47
Q

abnormal narrowing of spinal canal occuring most commonly in lumbar region

A

spinal stenosis

48
Q

neurogenic claudication

A

spinal stenosis

49
Q

extension of lumbar spine (standing walking uprigh narrows spinal canla worsens symptoms

A

spinal stenossi

50
Q

walking uphill/leaning on stroller / shopping cart: lumbar flexion reliees pain

A

spinal stenosis

51
Q

spinal stenosi causes narorwing of spinal canal due to intervertebral disc herniation, ligamentum flavum _____

A

ligamentum flavum hypertrophy,

and osteophyte formation affecting facet joints

52
Q

latissimus dorsi innervated by

A

thoracodorsal nerve

primary function: extension adduction medial rotation of humerus

53
Q

poor melanin formation in melaoncytes

A

albinism

54
Q

melanosome aggregates within cytoplasm of melanocytes

A

cafe au lait spots

55
Q

LEMS vs MG

hyporeflexia, areflexia, autonomic symptoms (dry mouth, imptoence),

A

LEMS

56
Q

rotates the scapula upward

A

serratus anterior

57
Q

ige mediated degranulation vs ige independent mast cell activation

A

independent: following meds, including opioids, radiocontrast agents, antiboitics (vancomycin)

ige mediated: environmental exposures suchas foods or vespid stings

58
Q

serum sickness is 7-14 days after

A

ige medaited/independnt 1 hour after

59
Q

overuse injury of secondary ossficiation center of tibial tubercle

A

osgood schlatter disase

common cause of knee pain in young adolescent athletes

60
Q

osgood schlatter causes insertion of what on to what

A

patella on to tibial tuberosity.

repertive quad contraction: OSgood schallter

chronic avusion: causes proximal patellar tendon to separte

61
Q

separation of medial and lateral condyles of tibia

A

anterior intercondylar area

62
Q

carpal tunnel defined by carpal bones on dorsal surface and ___ on volar surface

A

transverse carpal ligament

63
Q

carpel tunnel contains

A

tendons of Flexor digitorum profundus + superficialis

flexor pollicis longus

64
Q

piriformis passes through

A

greater sciatic foramen

sciatic nerve cross below pirfiromis muscle

65
Q

piriforms does what

A

external hip rotation

66
Q

muscle injury or hypertrophy can compress sciatic nerve: sciatica: piriformis syndorme

A

sciatica: pain tingling numbness in buttocks along nervedistirubtion

67
Q

passes through lesser sciatic foramen and inserts on greater trochanter of femur

A

obturator internus

68
Q

evert foot

A

superifical peroneal nerve

69
Q

dorsiflexion of foot

toe extension

A

deep peroneal nerve

70
Q

loss of dorsal foot sensation

A

injury to commmon peroneal nerve

71
Q

loss of sensation at medial aspect of leg

A

saphenous nerve

72
Q

actin contain fibroblasts

A

myofibroblasts

73
Q

increased MMP and actin contain fibroblasts related to

A

contracture

74
Q

inadequte vascularizaiton during healing

A

ulceration

75
Q

wound dehiscne

A

rupturuing of preivous closed wound

insufficent granulatio and scar tissue

76
Q

strong Th1 mediated response

A

Il2, ifn gamma, il 12

seen in tuberculoid m. leprae
symptoms: small number of hypopigmented well damracted skin palques; decreased sensation

77
Q

more disseminated veriso of m. lepare is what repsosne

A

th2: il4, il5, il10; leprotamous leprosy

78
Q

pt’s with strong cd4 th1 immune repsone will have indurated nodule in lepromin skin test

A

tuberculoid leprsoy

79
Q

leprotamous leprsy tests negative to

A

lepromins kin test due to weak th1 mediatec cell immune repsone

80
Q

medial band like calcifciations

A

monckeberg medial calcific scelrosis

81
Q

multinucleated cells w intranuclear inclusiosn

A

vzv

82
Q

eosinophilic cytoplasmic inclusions

A

molluscum bodies

83
Q

in churg struss mononeuritis multiplex is common

A

asysmettic multifocal neuropahty due to vasculitis affeting epinerual vessels

uworld (14 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions