Motor System 2: Posture and Locomotion Flashcards

1
Q

What’s the difference between feedforward and feedback motor control?

A

Feedforward: anticipatory
Feedback: in response to error

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2
Q

What 3 spinal tracts are used for feedforward postural maintenance?

A

Reticulospinal
Vestibulospinal
Uncrossed corticospinal

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3
Q

What happens if a cat lifts its leg without a feedforward mechanism in place?

A

It stumbles, relying on feedback to correct for errors.

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4
Q

What is the information for feedback?

A

Proprioception.

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5
Q

What happens to extensor stretch reflexes after spinal transection? Flexors?

A

Extensors: Lower amplitude, less coordinated response.
Flexor: they go away completely

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6
Q

Where is the rubrospinal tract in the spinal cord? Is it part of the medial or lateral motor system?

A

Just anterior to the cross corticospinal tracts. It’s part of the lateral motor system.

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7
Q

Where are the medial and lateral vestibular nuclei?

A

in the dorsal, lateral-ish medulla

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8
Q

Where are the medial and lateral reticular nuclei?

A

Medial: pons
lateral: medulla

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9
Q

How do you know that a muscle contraction is anticipatory?

A

Muscles contract before muscles are actually bearing weight.

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10
Q

What’s a central pattern generator (CPG)? Where is it located?

A

Network that generates rhythmic movements. It’s located in the spinal cord at the level of the motor neurons that control the relevant limbs.

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11
Q

Is the drive from the brain to walk rhythmic?

A

No. The walking CPGs convert the signal into rhythmic signals.

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12
Q

How do brain signals for walking, specifically, get to the CPG?

A

Through the reticulospinal tract.

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13
Q

What happens if you put some spinal cord in a dish and add neurotransmitters that the reticulospinal tract would normally provide?

A

Rhythmic alternate firing of extensor and flexor motor neurons.

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14
Q

What actually composes the CPG?

A

Pre-motor interneurons that activate/repress eachother, with one module for flexors, one module for extensors.

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15
Q

Where, within a spinal cord cross section is the CPG located?

A

In the medial intermediate zone.

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16
Q

What’s a transcription factor expressed by a subset of CPG interneurons? (probably trivia)

A

Hb9

17
Q

What’s the MLR? What does it do?

A

Mesencephalic Locomotor Region. Initiates locomotion (walking).

18
Q

Where is the MLR? Where do its fibers travel?

A

Just inferior to the inferior colliculus. Fibers go to the reticular formation, then down to the CPG.

19
Q

Other than the MLR, what else is sending signals to the muscles for walking?

A

Visual cortex -> motor cortex -> crossed corticospinal

Cerebellum -> brain stem nuclei -> …muscles (for adjustment)

20
Q

What happens with increasing stimulation to the MLR?

A

Walk -> trot -> gallop. (which is interesting, because these are very different motions)

21
Q

Why does postural support (i.e. almost-hanging from a harness) help people regain ability to walk after spinal cord injury?

A

Probably because it minimizes aberrant postural feedback that would mess up the gait.