Module 04: Skeletal System Flashcards
What are the components of the skeletal system?
(1) Bones
(2) Cartilages
(3) Tendons
(4) Ligaments
This components gives the body the structure.
Bones
This component is made up of a strong flexible connective tissue that protects the joints and the bones.
Cartilages
This component connects the muscle to the bone.
Tendons
This component connects the bone to another bone.
Ligament
What are the functions of the skeletal system?
- Support: Provides structure and cradles the internal organs
- Protection
- Movement: Bones by its attachments to the tendons are used as levers
- Storage: The bones are reservoirs of minerals, specifically calcium and phosphate, which are distributed in their ionic form.
- Blood cell production: Hematopoiesis occur in the red marrow of certain bones
- Fat Storage: The fats are stored in the yellow marrow.
- Hormone Production: They produce osteocalcin
This is a hormone that helps regulate insulin secretion, glucose hemostasis and energy expenditure.
osteocalcin
These comprise the bones, cartilage, tendons, and ligaments of the skeletal system.
Connective Tissues
These are found in the extracellular matrix of tendons and ligament, which makes these structures very tough, like
ropes or cables.
Collagen Fibers
What comprises the extracellular matrix?
collagen, ground substance, and other organic molecules, as well as water and minerals, which are all dependent on the characteristic of the extracellular matrix
This is a tough, ropelike protein that helps in the bone’s structure.
Collagen
These are large molecules consisting of many polysaccharides
attaching to and encircling core proteins and form large aggregates and attract water
Proteoglycans
The extracellular matrix of the cartilage is composed of what?
(1)Collagen and Proteoglycans
This is relatively rigid, but it springs back to its original shape after being bent or slightly compressed à excellent shock absorber
Cartilage
The extracellular matrix of bone is composed of what?
(1) collagen and minerals, including calcium and phosphate.
How does the collagen and minerals help the extracellular matrix of the bone?
The ropelike collagen fibers lend flexible strength to the bone.
The mineral component gives bone compression (weight-bearing) strength.
These are minerals in the bone that is in the form of calcium phosphate crystals
hydroxyapatite
This classification of the bones are longer than they are wide;
examples are upper and lower limb bones.
Long bones
This classification of the bones are approximately as wide as
they are long; examples are the bones of the wrist and ankle.
Short Bones
This classification of bones have a relatively thin, flattened
shape; examples are bones of the skull and sternum.
Flat Bones
This classification of bones include the vertebrae and
facial bones, which have shapes that do not fit readily into the other three categories.
Irregular Bones
This long bone structure is also known as the shaft and is composed of compact bone tissues.
Diaphysis
This long bone structure is composed of ends spongy bone tissue. It is an articular cartilage that covers the epiphyses.
Epiphysis
What is the role of the epiphysis?
Reduce Friction
This long bone structure is the site of growth between diaphysis and epiphysis
Epiphyseal plate
This long bone structure is known as the center of
diaphysis red or yellow marrow.
Medullary Cavity
This long bone structure is the membrane around bone’s outer surface
Periosteum
This long bone structure is the membrane that lines medullary cavity
Endosteum
This bone contain cavities, such as the large medullary cavity in the diaphysis, as well as smaller cavities in the epiphyses of long bones and in the interior of other bones
Bone Marrow
The spaces of soft tissues in the bone marrow is _____________.
Marrow
This is the location of the hematopoiesis (red blood cell formation), which is prevalent in new born.
Red Marrow in the Diaphysis
In the latter, hematopoiesis decreases over time, which bones in the body can this be limitedly seen occurring?
Flat Bones and Long Bones like the femur
This is found in the outer part of diaphysis (long bones) and thinner surfaces of other bones
Compact Bone Tissue
This is the structural unit of the bone.
Osteon
The osteon includes or is constituted of what?
(1) Lamella
(2) Lacunae
(3) Canaliculus
(4) Osteocytes
(5) Central Canal
This is known as the rings of bone matrix
Lamella
This is known as the spaces between lamella
Lacunae
These are tiny canals that transport nutrients and remove waste
Canaliculus
This is the center of osteon that contains blood vessels
Central Canal
This is located at the epiphyses of long bones and center of other bones. It has no osteons
Spongy (Cancellous) Bone Tissue
This is a composition in the spongy bone tissue, which are interconnecting rods, and spaces that contain marrow.
trabeculae
These bone cells are responsible for the formation of bone and the repair and remodeling of bone.
Osteoblasts
These bone cells are cells that maintain bone matrix and form from osteoblast after bone matrix has surrounded it.
Osteocytes
These bone cells contribute to bone repair and remodeling by removing existing bone
Osteoclasts
This is the precedent cell (stem cells) that start bone cell formation/
Osteoprogenitor cells
How do osteoclasts remove the existing bone?
Bone Reabsorption
This is known as the formation of bone by osteoblasts
Ossification
Bone formation that occurs within connective tissue membranes is called _________________.
intramembranous ossification
Bone formation that occurs inside hyaline cartilage is called
______________________.
endochondral ossification
How does intramembranous ossification occur?
Intramembranous ossification occurs when osteoblasts begin to produce bone within connective tissue. Osteoblasts line up on the surface of connective tissue fibers and begin depositing bone matrix to form trabeculae.
Where the the intramembranous ossification happen?
Ossification centers
In this, the bone formation transpires within a cartilage model. The cartilage model is replaced by bone
endochondral ossification
This pertains to bone formation in the diaphysis of a long bone.
Primary ossification center
This pertains to the bone formation in the epiphysis
Secondary ossification center
What is the steps in endochrondral ossification
- Chondroblasts build a cartilage model, the chondroblasts become chondrocytes.
- Cartilage model calcifies (hardens).
- Osteoblasts invade calcified cartilage and a primary ossification center forms diaphysis.
- Secondary ossification centers form epiphysis.
- Original cartilage model is almost completely ossified and remaining cartilage is articular
cartilage.
This is the process by which osteoblasts deposit new bone matrix on the surface of bones between the periosteum and the existing bone matrix, the bone increases in
width, or diameter.
Appositional Growth
How does bone growth occur?
Bone growth occurs by the deposition of new bone lamellae onto existing bone or other connective tissue.
This is where growth occurs.
epiphyseal plate.
How does the bone grow in length?
Chondrocytes increase in number on the epiphyseal side of the epiphyseal plate. Then the chondrocytes enlarge and die à The cartilage matrix becomes calcified. The dying chondrocytes are replaced by osteoblasts. The osteoblasts start forming bone by depositing bone lamellae on the surface of the calcified cartilage.
This process pertains to the removal of existing bone by osteoclasts and deposition of new bone by osteoblasts. This occurs in all bones
Bone remodeling