Mo - The Immune System Flashcards
Which part of the immune system do NK cells belong to? Adaptive or innate?
Innate
Which part of the immune system do B and T cells belong to? Adaptive or innate?
Adaptive
In which kinds of organs does adaptive immunity commence?
Secondary lymphoid organs
Which part of the immune system do dendritic cells belong to? Adaptive or innate?
Innate
What do dendritic cells do? (simple)
Present antigen to T cells
When dendritic cells are (immature/mature), they can migrate from the blood or tissue to the secondary lymphoid organs.
Immature
Where do dendritic cells interact with naïve T cells?
In the secondary lymphoid organs
Where do dendritic cells become mature?
In the secondary lymphoid organs
Immature dendritic cells (uptake/present) the antigen
Uptake
Mature dendritic cells (uptake/present) the antigen
Present
In which way other than function and origin do complement and antibodies differ?
In timing, antibodies take longer because they’re a part of the adaptive immune system
Which complement pathway is activated first?
Alternative pathway
How many pathogens will one T cell receptor recognise?
One
Where do B lymphocytes develop?
Bone marrow
Where do T lymphocytes develop?
Thymus
What is a synonym for immunoglobulins?
Antibodies
Why is the B cell receptor an antigen receptor and an effector molecule?
Because it secretes antibodies
Will de T cell receptor ever be secreted?
No
Which lymphocytes express RAG enzymes?
B and T lymphocytes
Why is there so much diversity for B and T cell receptors?
Because of RAG enzymes
To which CD does MHC 1 bind?
CD8
To which CD does MHC 2 bind?
CD4
Which MHC do dendritic cells have?
MHC 1 and MHC 2
Which 2 signals are needed for the activation of T cells?
Specific antigen presentation and costimulation
What do Th1 cells do? (simple)
Activate macrophages
What do Th17 cells do? (simple)
Enhance neutrophil response
What do Th2 cells do? (simple)
Activate cellular and antibody response to parasites
What do ThFollicular helper cells do? (simple)
Make the affinity of B cell receptors go up
What do Tregulatory cells do? (simple)
Supress other effector T cells
Which types of T cells (helper/cytotoxic) have CD4?
Helper
Which types of T cells (helper/cytotoxic) have CD8?
Cytotoxic
By which part of the antibody are the antibody effector functions determined?
Fc tail
What does the third signal do, after the T cell has been activated?
Differentiate the T cell
