Mo - The Immune System Flashcards

1
Q

Which part of the immune system do NK cells belong to? Adaptive or innate?

A

Innate

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2
Q

Which part of the immune system do B and T cells belong to? Adaptive or innate?

A

Adaptive

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3
Q

In which kinds of organs does adaptive immunity commence?

A

Secondary lymphoid organs

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4
Q

Which part of the immune system do dendritic cells belong to? Adaptive or innate?

A

Innate

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5
Q

What do dendritic cells do? (simple)

A

Present antigen to T cells

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6
Q

When dendritic cells are (immature/mature), they can migrate from the blood or tissue to the secondary lymphoid organs.

A

Immature

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7
Q

Where do dendritic cells interact with naïve T cells?

A

In the secondary lymphoid organs

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8
Q

Where do dendritic cells become mature?

A

In the secondary lymphoid organs

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9
Q

Immature dendritic cells (uptake/present) the antigen

A

Uptake

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10
Q

Mature dendritic cells (uptake/present) the antigen

A

Present

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11
Q

In which way other than function and origin do complement and antibodies differ?

A

In timing, antibodies take longer because they’re a part of the adaptive immune system

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12
Q

Which complement pathway is activated first?

A

Alternative pathway

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13
Q

How many pathogens will one T cell receptor recognise?

A

One

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14
Q

Where do B lymphocytes develop?

A

Bone marrow

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15
Q

Where do T lymphocytes develop?

A

Thymus

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16
Q

What is a synonym for immunoglobulins?

A

Antibodies

17
Q

Why is the B cell receptor an antigen receptor and an effector molecule?

A

Because it secretes antibodies

18
Q

Will de T cell receptor ever be secreted?

19
Q

Which lymphocytes express RAG enzymes?

A

B and T lymphocytes

20
Q

Why is there so much diversity for B and T cell receptors?

A

Because of RAG enzymes

21
Q

To which CD does MHC 1 bind?

22
Q

To which CD does MHC 2 bind?

23
Q

Which MHC do dendritic cells have?

A

MHC 1 and MHC 2

24
Q

Which 2 signals are needed for the activation of T cells?

A

Specific antigen presentation and costimulation

25
What do Th1 cells do? (simple)
Activate macrophages
26
What do Th17 cells do? (simple)
Enhance neutrophil response
27
What do Th2 cells do? (simple)
Activate cellular and antibody response to parasites
28
What do ThFollicular helper cells do? (simple)
Make the affinity of B cell receptors go up
29
What do Tregulatory cells do? (simple)
Supress other effector T cells
30
Which types of T cells (helper/cytotoxic) have CD4?
Helper
31
Which types of T cells (helper/cytotoxic) have CD8?
Cytotoxic
32
By which part of the antibody are the antibody effector functions determined?
Fc tail
33
What does the third signal do, after the T cell has been activated?
Differentiate the T cell