Mo - The Immune System Flashcards

1
Q

Which part of the immune system do NK cells belong to? Adaptive or innate?

A

Innate

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2
Q

Which part of the immune system do B and T cells belong to? Adaptive or innate?

A

Adaptive

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3
Q

In which kinds of organs does adaptive immunity commence?

A

Secondary lymphoid organs

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4
Q

Which part of the immune system do dendritic cells belong to? Adaptive or innate?

A

Innate

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5
Q

What do dendritic cells do? (simple)

A

Present antigen to T cells

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6
Q

When dendritic cells are (immature/mature), they can migrate from the blood or tissue to the secondary lymphoid organs.

A

Immature

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7
Q

Where do dendritic cells interact with naïve T cells?

A

In the secondary lymphoid organs

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8
Q

Where do dendritic cells become mature?

A

In the secondary lymphoid organs

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9
Q

Immature dendritic cells (uptake/present) the antigen

A

Uptake

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10
Q

Mature dendritic cells (uptake/present) the antigen

A

Present

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11
Q

In which way other than function and origin do complement and antibodies differ?

A

In timing, antibodies take longer because they’re a part of the adaptive immune system

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12
Q

Which complement pathway is activated first?

A

Alternative pathway

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13
Q

How many pathogens will one T cell receptor recognise?

A

One

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14
Q

Where do B lymphocytes develop?

A

Bone marrow

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15
Q

Where do T lymphocytes develop?

A

Thymus

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16
Q

What is a synonym for immunoglobulins?

A

Antibodies

17
Q

Why is the B cell receptor an antigen receptor and an effector molecule?

A

Because it secretes antibodies

18
Q

Will de T cell receptor ever be secreted?

A

No

19
Q

Which lymphocytes express RAG enzymes?

A

B and T lymphocytes

20
Q

Why is there so much diversity for B and T cell receptors?

A

Because of RAG enzymes

21
Q

To which CD does MHC 1 bind?

A

CD8

22
Q

To which CD does MHC 2 bind?

A

CD4

23
Q

Which MHC do dendritic cells have?

A

MHC 1 and MHC 2

24
Q

Which 2 signals are needed for the activation of T cells?

A

Specific antigen presentation and costimulation

25
Q

What do Th1 cells do? (simple)

A

Activate macrophages

26
Q

What do Th17 cells do? (simple)

A

Enhance neutrophil response

27
Q

What do Th2 cells do? (simple)

A

Activate cellular and antibody response to parasites

28
Q

What do ThFollicular helper cells do? (simple)

A

Make the affinity of B cell receptors go up

29
Q

What do Tregulatory cells do? (simple)

A

Supress other effector T cells

30
Q

Which types of T cells (helper/cytotoxic) have CD4?

A

Helper

31
Q

Which types of T cells (helper/cytotoxic) have CD8?

A

Cytotoxic

32
Q

By which part of the antibody are the antibody effector functions determined?

A

Fc tail

33
Q

What does the third signal do, after the T cell has been activated?

A

Differentiate the T cell