Mo - Mucosal Immunology: Introduction Flashcards
1
Q
Why do we need special defense mechanisms for the epithelial lining of mucosal tissues?
A
Because it’s thin
2
Q
How many layers of mucus does the colon have?
A
2
3
Q
How many layers of mucus does the small intestine have?
A
1
4
Q
What can NOD2 mutations lead to?
A
IBD
5
Q
What does NOD2 normally do?
A
Recognises pathogens
6
Q
What does Vedoluzimab do?
A
Prevents lymphocytes from going back to the gut when activated
7
Q
Which immunoglobulins do mucosal B cells mostly make? (2)
A
IgM and IgA
