MMI133_Lecture6 Flashcards
3 types of Parasites
protozoa
metaoa
extoparasites
protozoa
one-celled eukaryotes
metazoa
multicellular animals (Helminths) round worms
forms of Protozoa
cyst
trophozoite
oocyst
Ectoparasites
free living bugs
tapeworms
cyst
form of a protozoa with a tough protective layer outside of cytoplasmic membrane
protects form inhospitable environments
trophozoite
growing form in many protozoa spp
no cyst wall just cytoplasmic membrane
oocyst
cyst for in protozoa for some types of bacteria
diarrhea
protozoans to know
Entamoeba histolytica
Giardia lamblia
Trichomonas vaginalis
Acanthamoeba
Cryptosporidium
Toxoplasma gondii
Trypanosoma
Leishmania
Plasmodium
Entamoeba histolytica
amoebic dysentry (bloody diarrhea)
eats RBC’s, flask-shaped ulcer formation in intestines
trophozoite + cyst forms
cysts high Cl resistance
Giardia lamblia
beaver fever
flagellate
flatulence, intestinal upsets, nausea, abdominal cramps diarrhea
cyst + trophozoite
cysts high Cl resistance
Trichomonas vaginalis (Trich)
person to person sexual infection
no cyst stage
in vagina + male urethra
intense itching,
person-person transmission
Acanthamoeba spp
cyst present in all dust
contact wearers
in eyes
cyste + trophozoite stages
Cryptosporidium parvum
cows, rats, dogs, cats - to people
chronic diarrhea - serious no matter who you are
need ZN stain
oocysts high Cl resistance
no good treatment
Toxoplasma gondii
cat life cycle
cat feces ingested
undercooked meat + contact with cat feces
serious for fetus in pregnant women (especially first trimester)
Trypanosoma
blood parasites, bug vectored
1 Trypanosoma gambiense/rhodesiense (african sleeping sickness)
2 Trypanosoma cruzi (chaga’s disease + kissing bug)
Trypanosoma cruzi is caused by…
reduviid bug/kissing bug
Leishmania spp
sandflies
live + develop in macrophages/immune cells
Plasmodium spp
malaria
no vaccine
4 main types
most dangerous type: Plasmodium falciparum
mosquito carries sporozoite in saliva which enters bloodstream+ liver
Plasmodium falciparum malaria
fever + chills
virulence factor protein PfEMP1
cerebral malaria (clumping + occlusion of blood vessels)
anemia
kidney failure
only sure fire way to stop Plasmodium falciparum malaria
bed net soaked in pesticide
all types of Plasmodium malaria are transmitted by
Anopheles mosquitoes
night biters