Mitosis and meiosis Flashcards
Schwann theory on mitosis
Cells come from cells
Virchow theory on mitosis
Cells arise through binary fission
Stages of mitosis
Prophase - metaphase - anaphase - telophase - cytokinesis
What happens in early prophase?
Condensing replicated chromosomes
What happens in late prophase?
Prometaphase
Microtubules emerge from centrosome at poles of mitotic spindle extend into nuclear region reaching chromosomes. Some of the spindle microtubules attach to kinetochores. Other spindle microtubules make contact with microtubules coming from opposite pole
What happens in metaphase?
Mitotic spindle is fully formed. Chromosomes midway between spindle poles
What happens in anaphase?
Two centromeres of each chromosome come apart, separating the sister chromatids. Proteins of kinetochores, powered by ATP, walk newly separated daughter chromosomes along microtubules towards opposite poles of the cell. Microtubules attached to kinetochores shorten. Spindle microtubules not attach lengthen. Poles move farther apart
What happens in S phase?
Interphase - each chromosome is duplicated by the cell
How many chromosomes are there after DNA synthesis?
46 chromosomes - 92 chromatids
Characteristics of mitosis
- Genetically identical cells
- Diploid cells
- Takes place throughout an organism’s lifetime
- Involved in asexual reproduction
Characteristics of meiosis
- Genetically unique cells
- Haploid cells
- Sexual reproduction
- 4 haploid cells produced
What happens during meiosis?
- Interphase: DNA replication
- Prophase 1: chromosomes join
- Metaphase 1: homologs align in centre of cell
- Anaphase 1: homologous chromosomes separated
- Anaphase 2: sister chromatids separate
What holds homologous chromosomes together?
Synaptonemal complex
Where does crossing over occur?
Between homologous chromosomes
Non-sister chromatids of homologous ch
Characterics of spermatozoa
23 chromosomes, n=1