Mitosis and meiosis Flashcards

1
Q

Schwann theory on mitosis

A

Cells come from cells

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2
Q

Virchow theory on mitosis

A

Cells arise through binary fission

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3
Q

Stages of mitosis

A

Prophase - metaphase - anaphase - telophase - cytokinesis

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4
Q

What happens in early prophase?

A

Condensing replicated chromosomes

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5
Q

What happens in late prophase?

A

Prometaphase
Microtubules emerge from centrosome at poles of mitotic spindle extend into nuclear region reaching chromosomes. Some of the spindle microtubules attach to kinetochores. Other spindle microtubules make contact with microtubules coming from opposite pole

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6
Q

What happens in metaphase?

A

Mitotic spindle is fully formed. Chromosomes midway between spindle poles

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7
Q

What happens in anaphase?

A

Two centromeres of each chromosome come apart, separating the sister chromatids. Proteins of kinetochores, powered by ATP, walk newly separated daughter chromosomes along microtubules towards opposite poles of the cell. Microtubules attached to kinetochores shorten. Spindle microtubules not attach lengthen. Poles move farther apart

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8
Q

What happens in S phase?

A

Interphase - each chromosome is duplicated by the cell

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9
Q

How many chromosomes are there after DNA synthesis?

A

46 chromosomes - 92 chromatids

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10
Q

Characteristics of mitosis

A
  • Genetically identical cells
  • Diploid cells
  • Takes place throughout an organism’s lifetime
  • Involved in asexual reproduction
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11
Q

Characteristics of meiosis

A
  • Genetically unique cells
  • Haploid cells
  • Sexual reproduction
  • 4 haploid cells produced
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12
Q

What happens during meiosis?

A
  • Interphase: DNA replication
  • Prophase 1: chromosomes join
  • Metaphase 1: homologs align in centre of cell
  • Anaphase 1: homologous chromosomes separated
  • Anaphase 2: sister chromatids separate
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13
Q

What holds homologous chromosomes together?

A

Synaptonemal complex

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14
Q

Where does crossing over occur?

A

Between homologous chromosomes

Non-sister chromatids of homologous ch

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15
Q

Characterics of spermatozoa

A

23 chromosomes, n=1

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16
Q

What is an egg?

A

A secondary oocyte in metaphase ii

17
Q

N number of zygote

A

2

18
Q

How many primary coccyges in ovary?

A

300,000

19
Q

What is produced by meiosis in males?

A

Spermatozoa

20
Q

How are secondary spermatocytes produced?

A

Spermatogonium undergoes mitosis twice to produce primary spermocyte (meiosis i) and then secondary spermatocyte (meiosis ii)

21
Q

What is a germ cell?

A

Any cell that gives rise to gametes

22
Q

What is a primordial germ cell?

A

Diploid cells that arise through mitosis. Arise in primitive streak and migrate via the gut of an embryo to the developing gonads. Once in gonads, they form oogonium (female fetus). At 7 months, oogonia turn into primary oocytes. In males, oogonium = spermatogonia

23
Q

What does ss mean?

A

Chromosome made from one chromatid

24
Q

What does ds mean?

A

Chromosome made from two chromatids

25
Q

True or false, germ cells can only undergo meiosis

A

False

26
Q

True or false, meiosis is only completed in females once the oocyte is fertilised?

A

True

27
Q

Do males run out of primary oocytes?

A

No