Mitochondria Flashcards

1
Q

The mitochondria is the site for what?

A

cellular respiration and energy production

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2
Q

The mitochondria can also be a producer of

A

reactive oxygen species which can react with other components of the cell

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3
Q

Describe how the mitochodria looks and what it consists of

A
  • double membrane structure

Consists of
-outer membrane
-outer membrane space
-Inner membrane (cristae)
-Matrix
each plays a role in cellular respiration

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4
Q

Cell respiration is what type of reaction?

A

oxidation and reduction reaction

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5
Q

Glucose vs oxygen, which is reduced or oxidized and what are the products

A

Glucose is oxidized to CO2
Oxygen is reduced to water

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6
Q

What happens to the energy releases by cellular respiration?

A

It is captured by ATP

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7
Q

After energy is captured by ATP, what is it then used for?

A

cellular metabolism

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8
Q

Mitochodria also plays a central role in

A

apoptosis (cell death)

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9
Q

How does the mitochondria play a role in apoptosis?

A

An increase in mitochondrial membrane
permeability causes the release of mitochondrial enzymes

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10
Q

Which organelle is the only one that has its own DNA

A

Mitochondria
mt-DNA

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11
Q

What are mitochondrial diseases?

A

A group of disorders caused by
dysfunctional mitochondria

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12
Q

Mitochondria are found in every cell of the human body except

A

red blood cells

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13
Q

Typically the disorders are caused by a mutation in the

A

mitochondrial DNA

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14
Q

What is the apoposis activating factor?

A

cytochrome C

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15
Q

Why do mitochondrial diseases often present with muscle weakness
and neuropathies?

A

These tissues present high energy demands. Any condition altering ATP production will cause them not to function properly

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