Miscellaneous Flashcards

1
Q

incidence equation

in 2 x 2, will be

A

new cases
pop at risk

a/a+b

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2
Q

attributable risk equaiton

A

incidence exposed - incidence unexposed

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3
Q

proportion attributbale risk eq

A

attributable risk

incidence exposed

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4
Q

easy to perform, doesnt compare outcomes
starts w populatin w

type of study

A

case series

dz

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5
Q

___ is timely/inexpensive
ideal for __ cx

some ____ bias
__ and __ bias
no ___

A

case control
rare

selection
recall/interviewer
follow up

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6
Q

__ is observational
provides ___
best study for ___

often have __ bias
factors may be ___
__ bias

A

cohort study
attributable risk
diagnosis

selection
poorly monitored
surveillance

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7
Q

___ is most reliable design
equal distribution of __
minimizes ___

__ detects a true difference
type 1 error is __
type 2 error is ___

A

RCT
risk factors
bias

power
falsepos
false neg

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8
Q

___ is for generalizability
increases ___
evalautes ___ evidence

problems w ___/__ bias

A

systematic review
precison
all

heterogeneity, publusher

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9
Q

-1 to -.7 is __ correkation
-.7-.4 is ___ correlation
.4-.2 is ___ correlation

.2 - .4 is ___
.4-.7 is ___ correlation
.7-1 is ___ correlation

A

strong neg
mod neg
weak neg

weak pos
mod pos
strong pos

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10
Q

an effect of one factor confused/distorted by effect of second factor is ___

look for significant __ bw groups

A

confounding

difference

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11
Q

data collection methods results in more complete acquistion in one group ccompared to the other is

A

interviewer bias

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12
Q

screening identifies an illness that WOULD NOT HAVE SHOWN CLINICAL SIGNS before pt death

looks like reduced ___, but more people being ___

A

overdiagnosis bias

mortality
dx

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13
Q

published literature is unrepresentative of completed studies

A

publication bias

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14
Q

cases/controls remember exposure/RF differently

occurs in __ and __ studies

A

recall bias

case control, retrospective

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15
Q

choice of pt introduces systemic difference between groups

occurs in __ study

A

selection bias

obersvational

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16
Q

odds ratio eq in 2x2

relative risk eq in 2x2

A

a/b / c/d

a/a+b / c/c+d

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17
Q

NNT eq

A

1/ARR

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18
Q

Average risk reduction equation

A

incidence in control - incidence in exposed

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19
Q

relative risk reduction eq

A

CER-EER

CER

20
Q

PPV eq

NPV eq

A

TP/TP+FP

TN/TN+FN

21
Q

Sensitivity eq

specificity eq

A

TP/TP+FN

TN/TN+FP

22
Q

method to dec confounding

A

subgroup analysis

23
Q

range of values that marks precision of point estimate

determines ___

does not include value reflecting ____

absolute risk difference of __

risk ratio of ___

A

confidence interval

statistical significance

no effect

0

1

24
Q

Phase 1 trial

___ volunteers

measures S/S/D

A

healthy

safety, SE, delivery

25
Phase 2 trial participants are ___ comparison to __/__ outcomes __/___
affected pt none/placebo efficacy/dosing
26
phase 3 trial includes ___ compares to __/__ outcomes for long terrm ___ or ___
affected pt placebo/standard tx follow up, SE
27
phase 4 includes ___ compares to ____ outcomes: long term __, E, G drug is already ____
affected pt standard tx safety, efficacy, generalizability FDA approved
28
Do not perform interventions that harm but do not benefit principle?
nonmaleficence
29
act in patients interest benefit of intervention outweighs risk principle?
beneficence
30
respect for individual pt has right to decide principle?
autonomy
31
treat all pt fairly pt loses right to decide if it ___ principle?
justice harms others
32
Informed consent pt must __ pertinent info describe P/R/B/A should be ___ Exceptions: implied in __ pt lacks ___ inconsistent w __/__ clouded by __ or __ or __ choices __ often minors: parent __ obtained adolescent ____
understand procedure, risks, benefits, alternatives consistent emegency decision making capacity values/past mood disorder, delusion, hallucination vary consent assent
33
competent pt has right to __, even w ___ __/__ does not overrule
own decisions, advance directives POA/family
34
__ always unacceptable
euthanasia
35
__ w intent to relieve pain/suffering tx is acceptable even if __
terminal sedation shortens life
36
futile care means not __ to do anything tha does not ___
obligated, benefit pt
37
HIPAA pt owns ____ must allow ___ exception potential to harm __ High likelihood of harming __
HCI release others self
38
duty to warn reportable dz like __/__/__ inform ___ ___ abuse __ abuse
STI/TB/hepatitis potential victims child elder
39
Adolescent consent determined by ___ all states permit __ and __ most states permit ___ and ___
state STI tx/dx contraception/pregnancy services
40
elements of informed consent C/D/U/V exceptions severe __ P children under __
competence disclosure understanding voluntariness infections prisoner 18
41
always use __ w cohort always use __ w case control
risk odds ratio
42
differences of study pops in systematic review
heterogeneity
43
inc screening dx a dz that would be later dx
lead time bias
44
more likely to pick up slow progressing diseases look for __ or __/___
length bias stages advanced/non advanced
45
Forest plot uses ___ significant if diamond does not cross ___ high __ indicates heterogeneity
relative risk 1 I2
46
percentage of people w disease that test detects percentage of people wout disease that test negative
sensitivity specificity
47
percentage of pop that tests positive for dz percentage of pop that tests negative
PPV NPV