Misc

Question 0

Which bacterial toxins are encoded by a lysogenic phage?

Answer 0

ABCDE
shigA-like toxin
Botulinum toxin (certain strains)
Cholera toxin
Diphtheria toxin
Erythrogenic toxin of Strep. pyogenes

Question 1

Patient with Hx of smoking presents with pneumonia, diarrhea, and confusion.

Answer 1

Legionella

Question 2

Describe Listeria monocytogenes’ laboratory characteristics.

Answer 2

Gram (+) rods, catalase (+), non-sporulating

Characteristic tumbling motility. Actin rockets to move from cell to cell.

Question 3

How is Listeria transmitted?

Answer 3

transmitted through unpasteurized milk, soft cheeses, deli meats, vaginal delivery.

Question 4

Disease caused by Listeria in normal, healthy individuals

Answer 4

mild gastroenteritis

Question 5

diseases caused by Listeria in pregnancy, neonates, immunocompromised pts?

Answer 5

Pregnancy: amnionitis, septicemia, spontaneous abortion.
Neonates: meningitis, granulomatosis infantiseptica
Immunocompromised: meningitis

Question 6

Why does Listeria cause granuloma formation in infants?

Answer 6

Listeria is phagocytosed by MΦs, but prevents intracellular killing by escaping from the phagosome before fusion with the lysosome. Streptolysin O and phospholipase C allow this escape.

Question 7

What Abx for Nocardia? Actinomyces?

Answer 7

oh, SNAP!
Sulfa drugs for Nocardia.
Actinomyces req’s Penicillin.

Question 8

What does S. aureus’ Protein A do?

Answer 8

Binds Fc portion of Ig to prevent complement fixation and phagocytosis.

Question 9

4 infections for which S. pneumoniae is the most common cause.

Answer 9

MOPS
Meningitis
Otitis media
Pneumonia
Sinusitis