Antimicrobials 1 Flashcards

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1
Q

block cell wall synthesis by inhibition of peptidoglycan cross-linking

A

anything that ends in “-cillin”, cephalosporins, aztreonam, and imipenem

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2
Q

block peptidoglycan synthesis

A

bacitracin and vancomycin

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3
Q

block nucleotide synthesis

A

SMX and TMP

sulfonamides (e.g. sulfamethoxazole) and trimethoprim (TMP)

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4
Q

mechanism of fluoroquinolones

A

block DNA topoisomerases

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5
Q

how does rifampin work?

A

blocks mRNA synthesis

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6
Q

mechanism of metronidazole

A

DNA damage

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7
Q

which drugs block the 30s ribosomal subunit

A

buy AT 30: aminoglycosides, tetracyclines

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8
Q

which Abx block the 50s ribosomal subunit

A

CELL at 50S: Chloramphenicol, Erythromycin (macrolides), Linezolid, cLindamycin + streptogramins

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9
Q

What are the streptogramins?

A

quinupristin and dalfopristin

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