Antimicrobials 1 Flashcards
block cell wall synthesis by inhibition of peptidoglycan cross-linking
anything that ends in “-cillin”, cephalosporins, aztreonam, and imipenem
block peptidoglycan synthesis
bacitracin and vancomycin
block nucleotide synthesis
SMX and TMP
sulfonamides (e.g. sulfamethoxazole) and trimethoprim (TMP)
mechanism of fluoroquinolones
block DNA topoisomerases
how does rifampin work?
blocks mRNA synthesis
mechanism of metronidazole
DNA damage
which drugs block the 30s ribosomal subunit
buy AT 30: aminoglycosides, tetracyclines
which Abx block the 50s ribosomal subunit
CELL at 50S: Chloramphenicol, Erythromycin (macrolides), Linezolid, cLindamycin + streptogramins
What are the streptogramins?
quinupristin and dalfopristin