Minerals Flashcards

1
Q

what does trace minerals depend on?

A

soil and water composition and food processing

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2
Q

what kind of mineral deficiencies are easy to miss?

A

mild deficiencies

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3
Q

most common result of children with mineral deficiency?

A

Failure to grow/thrive

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4
Q

hypercalcaemia leads to impaired:

A

kidney function (stones)
other mineral absorption
bone: osteoporosis

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5
Q

If blood calcium is too high, what releases?

A

Calcitonin from thyroid

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6
Q

If blood calcium is too low what releases?

A

Parathyroid and vitamin D

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7
Q

What is malignant hyperthermia? how triggered?

A
  1. muscle releases excess Ca2+, uncontrolled ATPase

2. happen in general anaesthesis: Rx: dantrolene, ice

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8
Q

Calcium upper limit?

A

2.5g/day

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9
Q

majority of phosphorus consumed as?

A

fertilizers/bone ash

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10
Q

where is body’s phosphorus store?

A

hydroxyapatite in bones

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11
Q

phosphorus in body?

A

DNA, RNA, ATP, phospholipids

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12
Q

hypophosphataemia symptoms?

A

muscle, neuronal dysfunction, RBC fragility

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13
Q

hyperphosphataemia symptoms?

A

diarrhoea

calcification of organs/soft tissues

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14
Q

Potassium best found in what foods?

A

fruits/veg: bananas

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15
Q

potassium toxicity:

A

stop the heart

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16
Q

potassium deficiency:

A

arrythmias, weakness

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17
Q

Sulfur requirements met how?

A

by consuming aminoacids with sulfur sidechains: cysteine and methionine

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18
Q

Where on body high in sulfur?

A

keratin in skin, hair, nails

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19
Q

Sodium RDI?

A

2300mg/day

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20
Q

excess sodium leads to?

A

hypertension, oedema

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21
Q

Chloride toxicity?

22
Q

Magnesium supports what 2 things mainly?

A

bone mineralisation

muscle contractions

23
Q

Magnesium is a co-factor in?

24
Q

What is epsom salt? use?

A

MgS04, use as laxatives

25
Does magnesium help with muscle cramps?
probably
26
Iron RDI women, vs. men
women: 18mg/day men: 8mg/day
27
Deficiency in iron results in?
Anaemia, body temp dysreg, pica
28
haemochromatosis signs?
skin pigmentation, cirrhosis, diabetes
29
Fe3+ or 2+ absorbed and used?
Fe2+
30
Irons absorption assisted by?
vitamin C
31
daily turn over in iron?
2-4mg
32
Hereditary haemochromatosis is what?
defect in iron carrying/storing protein leads to excess iron
33
Zinc: men or women need more?
men, 14mg vs/ 8mg women
34
zinc important in what enzyme?
insulin | sperm production
35
zinc deficiency leads to?
growth retardation
36
highest source of zinc?
oysters
37
copper is important because?
final electron carrier in oxidative phosphorylation
38
Two copper diseases are:
Menke's disease | Wilson's disease
39
What is Menke's disease?
X-linked: +++ copper storage, no release: sparse, wirey hair, defective ATP7a
40
Wilson's disease?
copper toxicity, overactive ATP7A
41
What is kayser-Fleischer ring?
copper deposition in ring around cornea: diagnostic
42
Manganese is key in what formation?
glycogenin for glycogen formation and initiates photosynthesis
43
What is ATP7A do?
copper transporter
44
Selenium needed to make?
T3 and T4
45
Selenium toxicity?
garlic breath | brittle hair/nails,
46
Selenium comes from?
soil
47
Chromium enhances?
insulin and glucose tolerance
48
Molybdenum for?
enzyme co-factor
49
Vitamin B12 contains?
cobalt
50
fluoride function?
maintain bone and teeth health
51
fluorosis symptoms?
pitting/discoloration of teeth