Glucose Flashcards

0
Q

NADH make how many kj/mol

A

220

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1
Q

ATP is how many kJ/mol?

A

30.5

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2
Q

Anaerobic metabolism of glucose makes how many ATP vs. aerobic?

A

Anaerobic: 2ATP
Aerobic: 32 ATP

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3
Q

Glucose is Aldose or ketose?

A

Aldose

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4
Q

Fructose is Aldose or ketose?

A

Ketose

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5
Q

Galactose is Aldose or ketose?

A

Aldose

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6
Q

GLUT 1 transporter is where?

A

universal

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7
Q

GLUT-2 important for?

A

liver and pancreas

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8
Q

GLUT 4 is where?

A

muscle and adipose

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9
Q

What GLUT is key to diabetic rise in glucose? why?

A

decreased insulin response, GLUT 4 doesn’t uptake glucose

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10
Q

Anaerobic glycolysis produces what?

A

lactate

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11
Q

Red Cells have mitochondria?

A

Nope.

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12
Q

Red cells aerobes?

A

Obligate Anaerobes

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13
Q

Gluconeogenesis generates glucose from?

A

glycerol

aminoacids

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14
Q

High fructose correlated with?

A

obsesity

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15
Q

Change in free energy for ATP hydrolysis?

A

-30.5kJ/mol

16
Q

1,3 bisphosphoglycerate
phosphoenolpyruvate
creatine
all have in common?

A

high-energy compounds

17
Q

NADH is storage molecule for most e- which equals?

18
Q

Aldotriose vs. ketotriose?

A

ketotriose has C=O in middle

19
Q

If too much glucose in vessels, what happens?

A

glycated blood vessels: prone to clots, decrease circulation

20
Q

How does body deal with glucose damage?

A

Replace enzymes every 3 days

replace RBCs every 120 days

21
Q

How does high glucose affect vision?

A

weak vessels

aneurysms
hemorrhage

22
Q

how to measure blood glucose on RBCs?

23
Q

Body uses D or L glucose?

24
What is special about GLUT 4?
It migrates to cell membrane in response to insulin to allow cell uptake of glucose
25
does muscle have glucose-6-pase?
Nope only liver and kidney
27
Glycolysis makes what two energy rich molecules?
ATP and NADH
28
What is the Cory Cycle?
switching carbons between glycogen in muscle through lactate and back to glucose in liver
29
What tissues relies on anaerobic glycolysis?
Retina | Red Cells
30
3 sources for gluconeogenesis:
Lactate Amino Acids Glycerol
31
Are Fatty acids ketogenic or glucogenic?
Ketogenic
32
What is Galactosaemia?
missing enzyme to change galactose into glucose, in infants who cannot digest mother's milk
33
fructose has how many carbons?
5 carbon ring, furanose
34
Fructose metabolism needs what?
aldolase enzyme
35
Fructose is bad why? 2 big reasons
1. does not elicit insulin from pancreas 2. no leptin from fat cells 3. does not suppress ghrelin
36
In the liver, glucose turned into? Fructose turned into?
Glucose: glycogen Fructose: fatty acids