MIDTERMS ANTIINFLAMATORY

Question 1

compound with pain blocking properties

Answer 1

analgesic

Question 2

only salicylates recommended for children

Answer 2

Choline magnesium trisalicylate and aspirin

Question 3

the most used analgesic/antipyretic drug for children.

Answer 3

Acetaminophen

Question 4

popular antiinflammatory agents block the inflammatory response but

with antipyretic (fever-blocking) and analgesic (pain-blocking)
properties.

Answer 4

Salicylates

Question 5

extracted from willow bark, poplar trees, and other plants by
ancient peoples to treat fever, pain, and what we now call inflammation

Answer 5

Salicylates

Question 6

Salicylates inhibit the synthesis of _____

Answer 6

prostaglandin

Question 7

a potent vasoconstrictor that
normally increases platelet aggregation

Answer 7

thromboxane A2

Question 8

, a vasodilator that inhibits
platelet aggregation

Answer 8

prostacyclin

Question 9

treatment of mild to moderate pain, fever,
including rheumatoid arthritis and
osteoarthritis

Answer 9

Salicylates

Question 10

Pharmacokinetics: Salicylates

Answer 10

absorbed directly from the stomach within 5 to 30 minutes

Question 11

can occur with high levels of aspirin; dizziness, ringing in the ears, difficulty hearing, nausea, vomiting, diarrhea, mental confusion, and
lassitude can occur

Answer 11

Salicylism

Question 12

Treatment of mild to moderate pain, fever, inflammatory
conditions; reduction of risk of transient ischemic attack or stroke;
reduction of risk of myocardial infarction

Answer 12

Aspirin

Question 13

Adverse Effects: Aspirin

Answer 13

Nausea, vomiting, heartburn, epigastric
discomfort, occult blood loss, dizziness, tinnitus, acidosis

Question 14

provide strong
antiinflammatory and analgesic effects without the adverse effects associated
with the corticosteroids

Answer 14

Nonsteroidal antiinflammatory drugs

Question 15

NSAIDs block two enzymes, known as

Answer 15

COX-1 and COX-2

Question 16

COX-1 turns _____ into
prostaglandins as needed in a variety of tissues.

Answer 16

arachidonic acid

Question 17

active at sites of
trauma or injury when more prostaglandins are needed,

Answer 17

COX-2

Question 18

its effects increases pain/inflammation

vasodilates

blocks platelet clumping

Answer 18

COX 2

Question 19

Relief of the signs and symptoms of rheumatoid arthritis
and osteoarthritis; relief of mild to moderate pain; treatment of primary
dysmenorrhea; fever reduction.

Answer 19

Ibuprofen

Question 20

treat moderate to mild pain and fever and often is used in place of the NSAIDs or salicylates. It has been the
most frequently used drug for managing pain and fever in children

Answer 20

Acetaminophen

Question 21

acts directly on the thermoregulatory cells in the hypothalamus to cause sweating and vasodilation; this in turn causes the
release of heat and lowers fever

Answer 21

Acetaminophen