Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

PHARMACO > MIDTERM ANTIPROTOZOAL > Flashcards

MIDTERM ANTIPROTOZOAL Flashcards

1
Q

caused by intestinal invasion of the trophozoite stage of the protozoan Entamoeba histolytica

A

amebiasis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

mosquito that is essential to the life cycle of Plasmodium

A

Anopheles mosquito

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

syndrome of quinine toxicity

nausea,
vomiting, tinnitus, and vertigo

A

cinchonism

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

protozoal intestinal infection that causes severe diarrhea

A

giardiasis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

skin, mucous membrane, or visceral infection caused by a protozoan passed to humans by the bites of sand flies

A

leishmaniasis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

protozoan that causes malaria in humans

A

Plasmodium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

opportunistic infection that occurs when the immune system is depressed;

A

Pneumocystis jiroveci pneumonia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

African sleeping sickness

A

trypanosomiasis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

a developing stage of a parasite, which uses the host for essential nutrients needed for growth

A

trophozoite

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

ANTIMALARIALS

A

chloroquine
mefloquine
primaquine
pyrimethamine
quinine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Four protozoal parasites s causes of malaria

A

Plasmodium falciparum
Plasmodium vivax
Plasmodium malariae
Plasmodium ovale

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

the most dangerous type of
protozoan.

A

Plasmodium falciparum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

causes a milder form of the disease

A

vivax

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

rarely seen, seems to be in the process of
being eradicated.

A

ovale

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

acting against the red blood cell phase of the life cycle)

A

schizonticidal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

acting against the gametocytes

A

gametocytocidal

17
Q

acting against the parasites that are developing in the mosquito

A

sporontocidal

18
Q

first drug found to be
effective in the treatment of malaria

A

Quinine

19
Q

They are indicated for the prevention of Plasmodium falciparum malaria
when chloroquine resistance has been reported

A

combine atovaquone and proguanil.

20
Q

the mainstay of antimalarial therapy for infections

A

Chloroquine

21
Q

a combination
therapy for the treatment of uncomplicated or severe malaria caused by
chloroquine-resistant strains

A

quinine and one of the following antibiotics

doxycycline
tetracycline
clindamycin

22
Q

increases the acidity of plasmodial food vacuoles, causing cell
rupture and death.

A

Mefloquine

23
Q

very old drug for treating malaria, similar to quinine,
disrupts the mitochondria of the Plasmodium.

causes death of
gametocytes and exoerythrocytic

A

Primaquine

24
Q

used in combination with agents that act more rapidly

acts by blocking the use of folic acid in protein
synthesis by the Plasmodium

A

Pyrimethamine

25
Q

inhibits nucleic acid synthesis, protein synthesis, and glycolysis in P. falciparum.

treat uncomplicated malaria

A

Quinine

26
Q

Pharmacokinetics: rapidly absorbed from the GI tract, with peak serum levels
occurring in 1 to 3 hours

A

Quinine

27
Q

adverse effects of antimalarial agents

A

Central nervous system (CNS) effects

Immune reaction effects

GI tract and the effects on CNS control

28
Q

Increased bone marrow suppression may occur if ____ are combined with pyrimethamine

A

antifolate drugs

29
Q

Treatment and prophylaxis of acute attacks of malaria

A

Chloroquine

30
Q

used to treat amebiasis

A

metronidazole and chloroquine

31
Q

a disease caused by a protozoan that is passed from sand
flies to humans

A

Leishmaniasis

32
Q

sand fly injects an asexual form of this flagellated
protozoan, called

A

promastigote

33
Q

caused by another flagellated protozoan,
This infection is
usually spread during sexual intercourse

A

Trichomoniasis

34
Q

Pharmacokinetics: available only as an oral suspension and is slowly absorbed
and highly protein bound in circulation

A

Atovaquone

35
Q

Pharmacokinetics: available orally for children with Chagas disease

A

Benznidazole

36
Q

Pharmacokinetics: is readily absorbed through the lungs

A

Pentamidine

37
Q

Drug–Drug Interactions:

can lead to increased bleeding

A

Metronidazole and
tinidazole

PHARMACO (19 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions