MIDTERM ANTIHELMINTH

Question 1

ANTHELMINTICS DRUGS

Answer 1

albendazole
ivermectin
mebendazole
praziquantel
pyrantel

Question 2

worms cause
diseases that range in severity from mild to potentially fatal

Answer 2

Nematodes

Question 3

y transmitted when the worm eggs are ingested, either by transfer by touching the eggs

Answer 3

Pinworms

Question 4

remain in the intestine, cause little discomfort ; itchings

Answer 4

Pinworms

Question 5

transmitted when eggs found in the soil are ingested. attach to the wall of the colon. In large numbers, they cause
colic and bloody diarrhea

Answer 5

Whipworms

Question 6

are transmitted as larvae found in the soil and
inadvertently ingested ; liver abscess

more damage to humans than most of the other
helminths

Answer 6

Threadworms

Question 7

most prevalent helminthic infection. occur wherever sanitation is poor. Eggs in the soil are ingested with
vegetables or other improperly washed foods.

cough fever pain

Answer 7

Ascaris

Question 8

found in the soil, where they hatch into a larva thatmolts

worms suck blood
from the walls of the intestine,

severe anemia

Answer 8

Hookworm

Question 9

segmented flatworms enter the body as
larvae that are found in undercooked meat or fish

live in intestine; weight loss distention

Answer 9

Cestodes

Question 10

disease caused by ingestion of the encysted larvae of the
roundworm Trichinella spiralis, in undercooked pork

Answer 10

Trichinosis

Question 11

infection of the blood and tissues by worm embryos,

severe swelling

Answer 11

Filariasis

Question 12

platyhelminthic infection by a fluke that is
carried by a snail

Answer 12

Schistosomiasis

Question 13

treatment of active lesions; porkworms

Answer 13

albendazole

Question 14

treatment of threadworm ;river blindness

Answer 14

ivermectin

Question 15

treatment for pinworms, whipworms, hook

Answer 15

mebendazolle

Question 16

treatment of schistosomes/flukes

Answer 16

praziquantel

Question 17

toxic drugs—
should be avoided in children

Answer 17

albendazole, ivermectin, and praziquantel

Question 18

Pharmacokinetics: available in the form of a chewable tablet, and a typical 3-
day course Antihelminth:

Answer 18

Mebendazole

Question 19

Pharmacokinetics: poorly absorbed from the GI tract, reaching peak plasma
levels in about 5 hours Antihelminth:

Answer 19

Albendazole

Question 20

Pharmacokinetics: taken in a series of three oral doses

Answer 20

Praziquantel

Question 21

poorly absorbed, and most of the drug is excreted unchanged
in the feces

Answer 21

Pyrantel

Question 22

Adverse Effects: not absorbed systemically, may cause abdominal discomfort, diarrhea, or pain

Answer 22

Mebendazole and pyrantel

Question 23

Adverse Effects: Renal failure and severe bone marrow depression are associated with

Answer 23

albendazole

Question 24

The effects of albendazole, which are already severe, may increase if the drug
is combined with

Answer 24

dexamethasone, praziquantel, or cimetidine. T