END (PPT) Flashcards
act to increase or decrease metabolic processes of cells
Hormone
known as master switchboard of neuroendocrine
Hypothalamus
excess levels of gh
Gigantism
thickening of bony surfaces
Acromegaly
binds to gh receptor but doesnt stimulate IGF-1 secretion
Pegvisomant
pegvisomant is administered by
Subcutaneously
inhibits release of GH, glucagon, insulin and gastrin
Somastotin
reduces symptoms caused by hormone secreting tumors
Octreotide
ADH is also known as
Vasopressin
stimulates milk ejection
Oxytocin
results from insufficient ADH
Diabetes Insipidus
a diabetes insipidus for nocturnal enuresis, hemophilia
Desmopressin
inner layer of AG
Adrenal medulla
what gland secretes norepinephrin and epinephrine into circulation
Adrenal Medulla
what gland produces glucocorticoids and mineralocorticoids
Adrenal cortex
what do u call the rise and fall of CRH and ACTH
Diurnal rhythm
target and bind receptors responsible for inflammatory and immunosupresive effects
Glucocorticoids
indicated for short term treatment of inflammatory idorders
glucocorticoids
glucocorticoids adverse effects on children:
growth retardation
increases sodium reabsorption; increase potassium
Mineralocorticoids
lack of thyroids hormone in infant
Cretinism
sever lack of thyroid hormone in adults
Myxedema
manmade thyroid hormone t4
Levothyroxine
what disease is incorporated with hyperthyroidism
Graves disease
new bone replacses oldbone tissue
Pagets disease
drugs preventing loss of bone density
Bisphosphonates
hormone regulating levels of calcium and phosphate
Calcitonin
increased hunger; cells cant use glucose
Polyphagia
loss of fluid and increased tonicity of blood
Polydipsia
heart attacks and strokes
Atheroscleoris
loss of vision
Retinipathy
MOTOR, SENSORY CHANGES IN FEET AND LEGS
Neuropathies
Renal dysfunction
Nephropathy
condition when body can produce enough insulin
Diabetic ketoacidosis
blood sugar below 40mg
Hypoglycemia
Types of insulin: Injected at start of a meal
Rapid acting
Types of insulin: injected 15-30 mins before a meal
Short-acting
Types of insulin: control glucose between meals
Intermediate/longacting
Types of insulin: once daily taken
Long acting
bind to potassium channels on pancreatic beta cells increase insulin secretion
Sulfonylureas
Examples of sulfonylureas:
Glimepiride (Amaryl)
Glyburide (DiaBeta; Micronase)
Glipizide (Glucotrol)
decrease blood glucose
Insulin
increase blood glucose
Glucagon
decrese insulin sensitivity; increase FFA formation
Growth hormone
increase insulin release; stimulate satiety center
incretins
increase glucose output from live and muscles; breakdown of fat to FFA
Catecholamines
blocks satiety signals; decr adiponectic release; increase fat synthisi, alter gastric motility
Endocannabinoid system