MIDTERM ANTIDEPRESSED NAKO

Question 1

deficiency of these substances in key
areas of the brain results in depression

Answer 1

biogenic amine

Question 2

drug that prevents the enzyme
monoamine oxidase from breaking down norepinephrine (NE),
serotonin (5HT), and dopamine (DA), leading to increased
neurotransmitter levels in the synaptic cleft;

Answer 2

monoamine oxidase inhibitor (MAOI)

Question 3

drug that specifically
blocks the reuptake of serotonin and increases its concentration in the
synaptic cleft

Answer 3

selective serotonin reuptake inhibitor (SSRI

Question 4

: drug that increases both
serotonin and norepinephrine concentrations

Answer 4

serotonin norepinephrine inhibitors (SNRIs)

Question 5

drug that blocks the reuptake of
norepinephrine and serotonin

Answer 5

tricyclic antidepressants (TCAs)

Question 6

amine found in food that causes vasoconstriction and raises
blood pressure

Answer 6

tyramine

Question 7

Antidepressants may be classified into four main groups:

Answer 7

tricyclic
antidepressants (TCAs),

monoamine oxidase inhibitors (MAOIs),

selective serotonin reuptake inhibitors (SSRIs),

serotonin norepinephrine
inhibitors (SNRIs).

Question 8

reduce the reuptake of 5HT and NE into nerves.

Answer 8

tricyclic antidepressants

Question 9

s inhibit presynaptic reuptake of the neurotransmitters 5HT and NE

Answer 9

TCAs

Question 10

sedative effects of these drugs may make them more effective in patients
whose depression is characterized by anxiety and sleep disturbances

Answer 10

TCAs

Question 11

If TCAs are combined with ______, the risk of
arrhythmias and hypertension is increased.

Answer 11

sympathomimetics or clonidine

Question 12

Inhibits presynaptic reuptake of norepinephrine and serotonin; anticholinergic at CNS and peripheral receptors; sedating.

Answer 12

Imipramine

Question 13

irreversibly inhibit
MAO, an enzyme found in nerves and other tissues

Answer 13

Monoamine oxidase inhibitors

Question 14

causes the release of stored NE from nerve
terminals

Answer 14

tyramine

Question 15

Treatment of patients with depression who are unresponsive
to other antidepressive therapy or in whom other antidepressive therapy
is contraindicated

Answer 15

Phenelzine

Question 16

group of
antidepressant drugs that specifically block the reuptake of 5HT with little to
no known effect on NE

Answer 16

Selective serotonin reuptake inhibitors

Question 17

The four SNRIs are

Answer 17

Pristiq

Cymbalta

Fetzima

venlafaxine

Question 18

y blocks the reuptake of NE, 5HT, and
dopamine

Answer 18

Bupropion