Micturition Disorders Flashcards
What nerve is responsible for PSNS innervation of the bladder, when activated causes urination?
Pelvic nerve
-also carries sensory information from the bladder wall)
What nerve is responsible for SNS innervation o the bladder and when activated causes bladder relaxation?
Hypogastric nerve
What nerve carries somatic motor fibers causing contraction of the external urethral sphincter?
Pudendal
Describe the urinary cycle??
Passive phase of filling
—> hypograstric activate B receptors allowing bladder stretching
—> activate a1-receptors of trigone and proximal urethra
Blocks PSNS
Active phase (voiding)
—> Reflex: stretch receptors to pelvic nerve to spinal cord, brain stem, stimulate PSNS
—> contraction of bladder wall
—>pudendal nerve decrease urethral sphincter tone (can be over ridden at cerebrum)
Large distended bladder
Difficult to express
Is this UMN or LMN bladder??
UMN —> detrusor areflexia and sphincter hyperreflexia
Large bladder, easily expressed, constantly leaks
Is this a UMN or LMN bladder?
LMN
Rx for UMN bladder?
Baclofen (antispasmodic, acts as inhibitory neurotransmitter and skeletal muscle relaxant)
What is detrusor-sphincter reflex dyssynergia?
With initiation of detrusor contraction, the urethral sphincter spasms
Rx for detrusor-sphincter reflex dyssynergia?
A-adrenergic blockers (phenoxybenzamine, prazosin, and tamulosin)
What is dysautonomia??
Rare disease whete the autonomic system is damaged
Affecting all systems
Usually presents and GI disease (ileus and dilated GI)
Poor prognosis
What causes detrusor atony?
Overfill (obstruction)
Large flaccid bladder
Neurological exam in normal
What is the RX for detursor atony?
Manual expression of the bladder
-usually is not persistent
What is detrusor instability/detrusor hyperreflexia?
Detrusor contraction during storage OR
Low compliance of detrusor
Clinical signs associated with detrusor instability/detrusor hyperreflexia ??
Pollakiuria, stranguria, and dysuria
What is the RX for detrusor instability/ detrusor hyperreflexia ???
Anticholinergic. — oxybutynin, imipramine, or dicyclomine
Causes relaxation of bladder wall