Crusting Skin Diseases Flashcards

1
Q

What are the primary keratinization disorders?

A
Zinc responsive dermatosis 
Sebaceous adentitis 
Primary idiopathic seborrhea (vit A resp) 
Schauzers comedo syndrome 
Ear margin dermatosis
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2
Q

What do you call dry skin with white to grey flakes or scales?

A

Seborrhea sicca

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3
Q

What do you call oily, greasy skin/ haircoat, of the with rancid odor, sticky, or yellow scales?

A

Seborrhea oleosa

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4
Q

T/F: seborrhea, crust, and scale are usually secondary to another process

A

True

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5
Q

What are the two types of zinc responsive dermatosis?

A

Syndrome 1
- decreased capacity to absorb zinc from intestines

Syndrome 2
- dietary deficiency (rare)

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6
Q

Clinical signs of zinc responsive dermatosis

A

Pruritus and scales/crusts

  • mouth, chin, eyes, ears
  • elbow, pressure points
  • scrotum, prepuce, vulva

Hyperkeratotic footpads

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7
Q

What is the treatment for zinc-responsive dermatosis??

A

Oral zinc usually required for life

Fatty acids: omega 3 and 6

Short term, low dose glucocorticoids

Treat secondary infection if present
Use keratolytic shampoos

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8
Q

Sebaceous adenitis is most commonly seen in what breeds?

A

Poodle, akitas, vizslas, samoyeds, and Belgium shepherds

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9
Q

Clinical signs of sebaceous adenitits?

A

Bilaterally symmetrical - prominent on face, head, pinnae, and trunk
Follicular casts

Ceruminous otitis externa
Some dogs have rat tail
Generally non-pruritic

Cats have multifocal annular lesions of scale, crust, broken hairs, hair cats, and alopecia

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10
Q

DDX for follicular casts?

A
Sebaceous adenitis Staphylococcal folliculitis 
Demodecosis 
Dermatophytosis 
Keratinization defect 
Follicular dysplasia 
Endocrinopathies
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11
Q

Treatment of adenitis

A

Keratinolytic shampoos

Omega 3/6 fatty acids

Retinoids
Cyclosporine if retinoids fail

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12
Q

How can you diagnose primary idiopathic seborrhea?

A

Exclude all other causes of seborrhea, scale, crust

Eliminate secondary factors (pyoderma, malassezia, dermatophytes, mites)

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13
Q

Treatment of primary idiopathic seborrhea?

A
Oral vit A 
—inhibit sebum production 
— decreases keratin proliferation 
— stimulates humoral and cellular immunity 
—anti-inflammatory

Shampoos

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14
Q

What type of shampoo would you use with a primary idiopathic seborrhea with dry skin/haircoat ?

A

Use moisturizing Hampton — chlorhexiderm, allergroom, epi-soothe, etc

Emollient to coat with lipid
— humectant will draw water into epidemics from dermis (humiliation or hydra-pearls)

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15
Q

What type of shampoo would you use with a primary idiopathic seborrhea with oily skin/haircoat ?

A

Degreaser

— sebalyt, sebbafon, oxydex, selsun blue

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16
Q

What is a inherited dysplasia of the hair follicle resulting in the formation comedones (blackheads)0 on the back

A

Schnauzer comedo syndrome

17
Q

What lesions do you see in schnauzer comedo syndrome?

A

Secondary folliculitis and furunculosis

18
Q

How can you treat schauzers comedo syndrome?

A

Can’t be cured

Regular antiseptic and anti-seborrhea shampoo
Humectants after shampoo
Topical benzoyl peroxide gel
Isotretinoin

19
Q

What is ear margin dermatosis?

A

Scaly condition of ear margins
Follicular casts and partial alopecia

Many affected breeds have pendulous ears

20
Q

Who is the poster child for ear margin dermatosis

21
Q

What is the RX for ear margin dermatosis?

A

Moisturizing agents
Topical sulfur salicylic acid shampoo
Topical glucocorticoids

For complicated case: pentoxifylline

22
Q

What are the underlying causes of superficial necrolytic dermatitis (SND)

A
Hypoaminoacidemai 
Diabetes mellitus 
Chronic liver disease 
Phenobarbital hepatotoxicity 
Pancreatic glucagonoma (rare)
23
Q

What is the signalment of superficial necrolytic dermatitis? What is the most common locations ?

A

Mean age 10yrs
Smaller breeds most often

Onset of skin disease BEFORE clinical signs of hepatic/pancreatic disease

Footpads 100% involved
Mucocutaenous junctions involved in about 50%
Legs, hocks, elbow, ear pinna

24
Q

How does superficial necrolytic dermatitis?

A

Hyperkeratotic, crusty, cracking footpads

Erythema, scaling, crusting, erosive
Distal limbs, mouth, eyes, ear pinnae, elbow, hock, genitalia, ventral area, oral cavity

Secondary bacterial or yeast infections

25
How do you diagnose superficial necrolytic dermatitis?
Hemogram and blood chem profile - can be normal - increased ALT, ALP, AST, bili - decreased BUN, albumin, glucose Abd US: unique ‘honey-comb’ pattern in liver or mass in pancrease Biopsy lesions
26
What is a self-induced traum of the skin through excessive licking and chewing
Acral lick granuloma
27
What is the treatment for an acral lick granuloma?
``` Treat underlying cause Treat secondary bacteria Topical analgesia/physical barrier/bad tasting preparations Steroids? Tricyclics antidepressants Serotonin re-uptake inhibitors ```
28
Pathogenesis of idiopathic lipoid onychodystrophy?
Lupus-like disease resulting in claw loss | Highest in young adult and middle age dogs
29
Clinical signs of idiopathic lipoid onychodystrophy
Acute nail loss on all claws Nails are deformed, brittle with secondary infection
30
What other claw abnormalities do you rule out to diagnose idiopathic lupoid onychodystrophy ?
Bacterial paroncyhia, primary or secondary Broken or torn mail Neoplasia — SCC, subungual keratochanthoma, melanoma, fibrosarcoma Immune mediated
31
What is the diagnosis and treatment for idiopathic lupoid onychodystrophy
Histopathology Amputation P3/dewclaw ``` Treat secondary infections Essential fatty acids, vit E Improvement within 3-4months If no improvement -niacinamide/tetracycline -steroids ```