Microbiology - Helminths Flashcards

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0
Q

Platyhelminths =

A

flatworms

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1
Q

Nematodes =

A

Roundworms

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2
Q

Name three roundworms who’s life cycle involve a larval form that migrates through the tissue and into the lung

A

1 Ascaris lumbricoides
2 Necator americanus
3 Strongyloides stercoralis

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3
Q

Necator americanus mode of transmission?

A

This long, slender fiariform larva can penetrate skin.

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4
Q

When larva of Strongyloides stercoralis hatch in the small intestine, they can do three different things. What?

A

1 Autoinfection - penetrate the intestines directly -> then go to lung
2 Direct cycle - passed in feces. Penetrate the skin of new host
3 Indirect cycle - Larvae are passed in stool. Then lay eggs in soil which must hatch to infect new person.

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5
Q

Ascaris lumbricoides and Necator americanus have very similar life cycles. How do they differ?

A

Ascaris - moves from intestines to lung.

Necator - moves from foot(penetrate skin) to lung.

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6
Q

How do Trichinella infection occur?

A

Ingestion of raw/undercooked pork.

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7
Q

Trichuris trichiura =

A

whipworm

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8
Q

Enterobius vermicularis =

A

Pinworm

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9
Q

Enterobius vermicularis and Trichuris trichiura life cyles?

A

Both have very simple life cycles. Transmission occurs by infestion of eggs. These eggs hatch in the small intestine.

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10
Q

What ass-related manifestation occurs with Enterobius vermicularis infection?

A

Female pinworm migrates to the perianal area(usually at night) to lay her eggs. This causes severe perianal itching!

Enterobius vermicularis = itchy asshole!

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11
Q

Blood and tissue nematodes route of spread?

A

Bite of an arthropod.

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12
Q

How is Ochocera volvulus spread?

A

By infected black flies.

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13
Q

Manifestations of Onchocerca volvulus infection?

A

1 Skin lesions that are intraepithelial granulomas = lizzard skin
2 Microfilariae migrate to the eye causing blindness.

Onchocerca volvulus = a blind lizzard

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14
Q

Wuchereria bancrofti & Brugia malayi, type of infection and clinical manifestation?

A

Both cause lymphatic infection and can result in chronic leg swelling.

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15
Q

Dracunculus medinensis?

A

Guinea worm

16
Q

How do Schistosoma infect humans?

A

Penetration of skin.

17
Q

How do schistosomes avoid human immune system?

A

Molecular mimicry

18
Q

3 clinical manifestations of schistosomiasis?

A

1 Dermatitis - as the fluke penetrate a swimmer’s skin.
2 Katayama fever - as the adult schistosoma starts laying eggs.
3 Chronic fibrosis - due to granuloma formation around eggs.

19
Q

Diphyllobothrium latum =

A

Fish tapeworm. Can grow to 45 meters in length, and may absorb a significant amount of vitamin B12.