Microbiology - chapter 7 - Corynebacterium and Listeria Flashcards
Where do the corynebacterium diphteria first infect?
In the pharynx where it form a greyish pseudomembrane
Corynebacterium Diphteria and Listeria monocytogenes are especially associated with what group of patients?
th pediatric age group
What is the pseudomembrane made by corynebacterium composed of?
fibrin, leukocytes, necrotic epithelial cells and corynebacterium diptheriae cells
Dark inflammatory exudate in the pharynx of a child.. DD?
strep throat and corynebacterium D. Corynebacterium is darker and thicker than the strep infection.
3 step method to treat corynebacterium diphteriae?
1 antitoxin - to prevent damage to heart and nervous system
2 Penicilin or erythromyocin
3 DPT vaccine
Corynebacterium diphteriae have a powerful exotoxin. Discribe the A and B subunit of this toxin.
B subunit - binds to target cells and allows for A subunit to enter cell.
A subunit - blocks proteinsynthesis by inactivating elongation factor(EF2), as a antibiotik against human cells.
what is a nosocomial infection?
hospital aquired infection
upper lobe lung nodules and cavities that form air-fluid levels are charracteristic of this baterium?
Rhodococcus equi, formerly known as corynebacterium equi.
What list lists subjects who get listeriosis?
This list:
1 pregnant woman
2 neonates
3 meningitis in elderly and immunocompromised
when and why, in a the course of pregnancy, do listeria infection most often occur?
third trimester, when cell-mediated immunity decreases. 22% of these infections results in neonatal death.
dietary restriction to avoid listeriosis during pregnancy?
stay away from cold cuts and soft cheese
Three organisms that cause neonatal meningitis?
listeria monocytogenes, Escheria coli and group B streptococcus
second most common cause of meningitis, after pneumococcus, in people over 50?
Listeria monocytogenes
