Microbiology - chapter 11 - Haemophilus, Bordetella and Legiionella Flashcards
What type of Haemophilus influenzae is commonly associated with invasive disease in children?
Hemophilus influenzae with capsule b(virulence factor)
capsule b = bad for children
Haemophilus influenzae, Bordetella pertussis and Legionella pneumophilia are all aquired through..?
Through the respiratory tract.
Two bacteria associated with meningitis in children age 6 months to three years?
Haemophilus influenzae and Neisseria meningitides.
Hey! Teachers! Leave them kids alone! All in all…
What are the HACEK organisms?
HACEK are slow growing organisms known to cause endocarditis.
Hemophilus species Actinobacillus species Cardiobacterium species Eikenella species Kingella species
Four major virulence factors of Bordetella pertussis?
1 Pertussis toxin - activate adenylate cyclase(on is on forever)
2 Extra cytoplasmic adenylate cyclase - lowered H2O2 & superoxide
3 Filamentous hemagglutin - pili rod(adehesin)
4 Tracheal cytotoxin - destroy ciliated epithelial cells
Three stages of whooping cough?
1 Catarrhal stage - 1 to 2 weeks, low grade fever, sniffles & sneeze.
2 Paroxysmal stage - lating a moth++, non productive cough.
3 Conalescent stage - resolution.
In what environment do Legionella pneumophilia thrive?
Water, H20, aqua & wody.
Two pathologies produces by Legionella pneumophilia?
Pontiac disease - flu like symptoms. Headache, muscle aches, fatigue, fever & chills.
Legionnaires disease - high fever and severe pneumonia.
Legionella haemophilus can produce disease ranging from mild asymptomatic infection to severe pneumonia.