Microbio Parasitology

Question 0

Bloody diarrhea/dysentery, liver abscess with anchovy paste exudate.

Etiology, T, Dx, Tx

Answer 0

Entamoeba histolytica
T: cysts in water
Dx: serology trophozoite with RBC in cytoplasm
Cyst with multiple nuclei in stool
Tx: metronidazole; iodoquinol for asx cyst passers

Question 1

Bloating, flatulence, foul smelling, FATTY diarrhea seen in campers or hikers

Etiology, T, Dx, Tx

Answer 1

Giardia lamblia
T: cysts in water
Dx: trophozoite or cyst in stool
Tx: metronidazole

Question 2

Protozoa causing GI infections

Answer 2

G lamblia
E histolytica
Cryptosporidium

Question 3

Protozoa causing hematologic infections

Answer 3

1 plasmodium sp

2 babesia sp

Question 4

48 hour cycle fever (tertian fever) with dormant form in liver

Answer 4

P vivax / ovale

Question 5

Severe irregular fever patterns with parasitized RBCs concluding capillaries in the brain, kidney and lungs

Answer 5

P Falciparum

Fatay ka!

Question 6

72 cycle fever (quartan)

Answer 6

P malaria

Question 7

Plasmodium spp

T, Dx, Tx

Answer 7

T anopheles mosquito
Dx blood smear: trophozoite ring form
RBC schizont w merozoites
Tx chloroquine - blocks heme polymerase. Mefloquine if resistant
Life threatening IV quinidine
Vivax ovale primaquine for hypnozoite ( h for hepatic)

Question 8

Ixodes tick is carrier of 2

Answer 8

1 Borrelia burgdorferi
2 Babesia sp - dx Maltese cross, PCR
tx atovaquone + azithromycin

Question 9

Protozoa CNS infections

Answer 9

1 toxoplasma Gondi
2 naegleria fowleri
3 trypanosoma brucei/gambiense/rhodiense

Question 10

Ring enhancing brain lesions on CT or MRI
Or
Chorioretinitis+hydrocephalus+intracranial calcifications

Answer 10

Toxoplasma Gondi

T cysts in meat or cat feces
Dx serology, biopsy
Tx sulfadiazine + pyrimethamine

Question 11

Amoebas in spinal fluid

Answer 11

Naegleria fowleri

• rapidly fatal meningoencephalitis
• swimming in freshwater lakes, enter via CRIBRIFORM plate
• amphotheracin

Question 12

African sleeping sickness
Or
Enlarged lymph nodes

Answer 12

African sleeping sickness -
Or
Enlarged lymph nodes - T brucei (bayag)

T tsetse fly, painful bite
Dx blood smear
Tx suramin - blood borne ds
Melarsopol - for CNS penetration

Question 13

Only malaria that causes cerebral involvement

Answer 13

P falciparum

Question 14

Macrophage containing amastigotes

Answer 14

Leishmania donovani via sandfly