Micro zoonosis Flashcards
Compare and contrast the epidemiology of infections caused by Brucella, Bartonella, Pasteurella, and Erysipelothrix. Identify the pathogenesis of infections caused by Brucella, Bartonella, Pasteurella, and Erysipelothrix.
Small gram negative non-motile coccbacilli
brucella
grows on erythiritol
brucella
brucella positive for what chemiical tests
catalase and oxidase
virulance factors for brucella
endotoxin, supression of ixygen killing in PMNs, inhibit killing within macrophaes and phagocytes
disease that causes contagious abortion and sterility in animals
brucellosis
causes an initial rise in IgM then IgG
brucellosis
brucellosis spread in body
local abcess –> regional lymph nodes –> liver spleen, bone marrow and kidneys
forms granulomas in infected tisses
brucellosis
multiply within phagocytes of the RES
brucellosis
flu like sx, anorexia, back pain, hepatosplenomegally and intermittent fever
brucellosis
sx of brucellosis occur how long after infection
2-8 weeks
complications of brucellosis infection
GI inflammation, other systmenic. common chronic fatigue and mental depression
best human tissue to culture brucellosis
bone marrrow
anibiotic for brucellosis
doxy, w/o stroptomycin or rifampin
prevention of brucellosis
avoid unpastuerized milk, protective clothiing for slaughterhouse workers
B quinana causes
trench fever
B henselae causes
cat scratch fever
b baciliformis causes
oroyo fever
where do you find oroyo fever
peru, ecuador and colombia
small gram negatve aerobic bacilli
bartonella
vector is he body louse
trench fever
sudden onset chills, relapsing fever, headache, and maculopapularrash on trunk and abdomen lasting up to a month
trench fever
occurs in homeless chronic alcoholics in the US and france
trench fever
most common cause of benign lymphademea in kids and young adults
cat scratch fever
lyphadenopathy in upper part of body, skin rashes and inoculation papule
cat scratch fever
antimicrobial for cat scratch fever
rifampin
proliferative disease of small blood vessles seen in AIDS and other immunocompromised pts
bacillary angiomatosis
purple-red nodular lesion consisting of proliferating vascular tufts, loose collagen stroma and PMN infiltrate
bacillary angiomatosis
treatment of bacillary angiomatosis
erythromycin or doxy
gram negative, nonmotile, non-spore forming coccobacilli
pasteurella
virulance factor of pasteurella
encaspsulation prventing phagocytosis
presnet in nasopharynx of cats, dogs, swine and rats
pasteurella
infection from bites and licks from cats and dogs
pasteurella
most common pathenogen from cat bites
pasterella
localized cellulitus and lymphademitis leading to microabcesses and hemorragic lesions in lungs, meniges, joints and bones
pasterella
focal soft tissue infection after animal bite, ot chronic resp infection, ot baceremia accompanied by metastatic lesions
pasteurella
endocarditis is a complication of
pasteurella, erysipeilothrix
ID’d in sputum, pus or SCF
pasteurella
DOC for pasteurella
penicillin
gram positive bacillis non-motile and non-spore forming
erysipeilothrix
easilt culured from blood
erysipeilothrix
distinguishes erysipeilothrix from listeria
catalase +
found in swine and mucus of fish
erysipeilothrix
local skin cellulitis, leading to multiple skin lesion, possible brain lesion, bone infection and chronic arthritis
erysipeilothrix
DOC for erysipeilothrix
penicillin
