Measles and such

Question 1

morphology of measles virus

Answer 1

enveloped, negative sense, single stranded RNA virus with 6 structural proteins

Question 2

location of measles replication

Answer 2

cytoplasm

Question 3

giant cells indicitve of

Answer 3

measles

Question 4

transmisson of measles

Answer 4

respiratory droplets

Question 5

tract of infection of measles

Answer 5

resp tract –> lymphatics –> spleen –> blood stream

Question 6

measles virus infects what tissues

Answer 6

all epithelial cell surfaces

Question 7

abrupts onset of illness with cough, coryza, rhinorrhea, photophobia, and conjuctivitis

Answer 7

measles

Question 8

lesions on buccal mucosa with red halo (koplik’s spots)

Answer 8

measles

Question 9

koplik spots precede measles rash how long?

Answer 9

12-24 hours

Question 10

maculopapular lesions

Answer 10

measles

Question 11

sickest day of measles

Answer 11

day rash appears

Question 12

causes measles rash

Answer 12

T-cell response to measles virus antigens in endothelial cells of skin capillaries

Question 13

measles complications

Answer 13

giant cell pneumonia
encephalitis
SSPE
atypical measles
secondary bacterial pneumoia

Question 14

fatal , non rash measles complication in people with defective cell mediated immunity

Answer 14

giant cell pneummonia

Question 15

CNS issue, myoclonic jerks, photophobia, blindness, coma 6-15 years after measles infection

Answer 15

SSPE

Question 16

conplication form killed measles virus

Answer 16

atypical measles

Question 17

where you can grow measles virus

Answer 17

monkey kidneys or human cell cultures

Question 18

easiest and efficient way to confirm measles

Answer 18

immunoflouracense assay for in cells harvested from mucus, urine, and skin biopsies

Question 19

giant cells on giemsa stain

Answer 19

measles

Question 20

treatment for early exposure to measles

Answer 20

pooled immunolobulin or vaccination witin 2/3 days of exposure

Question 21

acute, painful parotitis

Answer 21

mumps

Question 22

paramyxoviruses

Answer 22

measles/mumps

Question 23

out of respiratory sites of mumps

Answer 23

testes, meningies, pancreas and ovaries

Question 24

where you can row mumps virus

Answer 24

monkey kidneys

Question 25

multinucleated giant cells

Answer 25

mumps

Question 26

sites of recovering mumps virus from pts

Answer 26

saliva, urine, pharynx, secrections from Stensen's duct, and CSF

Question 27

1/3 of infections are subclinical

Answer 27

mumps

Question 28

can cause congenital defects in infected pregnant mothers

Answer 28

rubella

Question 29

togavirus

Answer 29

rubella

Question 30

envoloped, positive sense, single stranded RNA virus with icosahedral nucleocapsid

Answer 30

rubella

Question 31

ranges from inapparent infection to lymphedenopathy, mild malaise, corzya, low-grade fever and rash

Answer 31

rubella

Question 32

irregular pink, maculopapular lesions starting on the face, spreading to the trunk and lasting 3 days

Answer 32

rubella

Question 33

adult femals with polyarthritis and polyarthalgia

Answer 33

rubella

Question 34

diagnosis of rubella

Answer 34

specific IgM antibody (in green monkey kidneys)

Question 35

reinfection can occur in immune folks

Answer 35

rubella

Question 36

vaccination contraindicated in pregnant women

Answer 36

rubella

Question 37

time in pregnancy most vunreable to congenital rubella infection

Answer 37

first 20 weeks

Question 38

baby sx of congenital rubella

Answer 38

cararacts, MR, deafness, heart defects, microcephaly, and rash

Question 39

"bluberry muffin baby"

Answer 39

congenital rubella

Question 40

place to detect rubella virus in baby

Answer 40

CSF, urine, rectal swab

Question 41

serodiagnostic of in utero infection of rubella

Answer 41

IgM in cord serum

Question 42

time kids born with CRS should be considered infectious

Answer 42

1 year

Question 43

icosahedral visur with no capsid

Answer 43

B19 parvoviruses

Question 44

fifth disease virus type

Answer 44

B19 parovirus

Question 45

pathenogenisis of congenital rubella

Answer 45

affects normal growth, mitosis, and chromosomal structure in cells

Question 46

distinct non vesicular rash on cheeks, resembing a slap with polyarthritis,

Answer 46

fifth disease

Question 47

can cause aplastic crisis

Answer 47

fifth disease

Question 48

fatal parvovirus infection in fetus

Answer 48

hydrops fetalis

Question 49

virus that spreads to bone marrow

Answer 49

B19 parovirus

Question 50

dianosis of b19 parvovorus

Answer 50

IgM or viral DNA by PCR

Question 51

big-ass 2x stranded DNA virus

Answer 51

pox

Question 52

reolicates it;s genome and assembles virons in cell cytoplams with large cytoplasmic inclusions

Answer 52

pox

Question 53

difference between pox viruses and chickenpox

Answer 53

all skin lesions are the same stage in development in pox diseases

Question 54

variola causes

Answer 54

smallpox

Question 55

vaccina casues

Answer 55

cowpox

Question 56

replication site of pox

Answer 56

upper resp tract

Question 57

western/central africa pox virus

Answer 57

monkey pox

Question 58

sheep pox that can be transmitted to humans

Answer 58

orf virus

Question 59

clusters of wart lije viruses on the face

Answer 59

molluscum contagiosum

Question 60

diagnostic for molluscum contagiosum

Answer 60

large cytoplasmic inclusions