bone neoplasm Flashcards
1. Describe the most common types of carcinoma that metastasize to the bone 2. Describe the clinicopathologic features of common benign neoplasms (osteochondroma, enchondroma, giant cell tumor) 3. Describe the clinicopathologic features of common malignant neoplasms (osteosarcoma, chondrosarcoma, Ewing sarcoma)
most common types of cancer that met to bone
breast, lung, thyroid, kidney, prostate (BLT with a Kosher Pickle)
most commin sites of mets to bone
proximal femoral head/neck, and veterbral bodies
most common tumor of bone
osteochondroma
mushroom/brochollu shaped tumor around the knee in a young man
osteochondroma
medularry cavity of tumor contigious with medullary cavity of the bone
osteochondroma
blue cartilage cap
osteochondroma
benign, painless cartilaginous tumor in middle aged pts
endochondroma
radiographic stippling
endochrondroma
tumor resembling cartilagle
endochrondroma
signs that an endochromdroma is turning malignant
new onset of pain
cortical erosion or soft involvement
increased cellularity, evidence of invasive growth, necrosis
benign but locally aggressive bone neoplasm
giant cell tumor
long bone tumor in ages 25-40
giant cell
arises in the epiphysis w/extension into the metaphysis
giant cell
way to distinguish giant cell tumor from malignancy
stromal cells should be cytologically bland
most common primary bone malignancy
osteosarcoma
