metabolism 3 Flashcards

1
Q

where does the citric acid cycle occur?

A

mitochondrial matrix

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2
Q

does citric cycle require oxygen?

A

no but it is considered an aerobic process because it takes place in the presence of oxygen.

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3
Q

the pyruvate enter the?

A

matrix

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4
Q

in thepresence of nad+, pyruvate

A

oxidizes to form acetyl coA and produces 1 nadh for each pryvate oxidizing = 2

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5
Q

acetyl coa enters the

A

citric acid cycle

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6
Q

how many steps in the citric acid cycle?

A

8 and has 8 enzymes

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7
Q

how many nadh co2 atp and acetyl coa before the citric acid cycle?

A

4 nadh , 2 co2, 2 atp, and 2 acetyl coA

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8
Q

what was made after the citric acid cycle?

A

1 atp in step 5, 3 adh in steps 3,4,8, 1 fadh2 in step 6 and 2 co2 in step 3 and 4

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9
Q

how many times does the citric acid cycle go around oe molecule of glucose?

A

for each molecule of glucose, the citric cycle goes around 2x. so for one molecule of glucose, 2 ATP, 6 NADH, 2 FADH2, AND 4 CO2

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10
Q

has glucose been fully oxidized by this point?

A

yes

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11
Q

after the citric acid cycle, __ molecules of NADH and ___ molecules of FADH2 have been generated.

A

6 nadh and 2 fadh2

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12
Q

these molecules are carrying ?

A

high energy electrons with potential energy

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13
Q

this stored energy is used to drive atp synthesis in the process of?

A

oxidative phosphorylation

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14
Q

what happens. next?

A

the electrons are transferred from one electron carrier to another until they combbine with o2 and h to form h20.

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15
Q

where does etc occur?

A

inner membrane of mitochondria

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16
Q

the process by which atp is made from energy released by the etc is called

A

oxidative phosphorlyation: the use of redox reaxtions in an etc to produce the energy needed to attach pi to adp to make atp.

17
Q

the enzyme that makes atp from adp and pi is called

A

atp synthase

18
Q

this reaction is endergonic, where does the cell get the energy from?

A

ion gradient of h+ that exists across the inner mitochondrial membrane

19
Q

how is the h+ gradient generated

A

by the etc

20
Q

when the electrons are transferred from one carrier to the next,

A

a small amount of energy is released and that is used to pump h+ across the membrane from the matric to the intermembrane space

21
Q

the electron carriers pick up and release protons when they pick up electrons

22
Q

the h+ gradient that exists is called the

A

proton motive force

23
Q

after movement into the intermembrane space, there

A

is now an electrochemical difference across the inner membrane

24
Q

since h+ is an ion, it cannot diffuse across membrane on its own..

A

it passes through the channel formed by the atp synthase

25
making atp is a type of work?
chemical work what is the energy soruce?? proton gradient formed by the etc aka pmf
26
what is chemiosmosis?
an energy coupling mechanism that makes use of proton gradient to drive cellular work: - mitochondria uses it to make atp - planrs use it to transport molecules proton pump - bacteria use it to rotate flagella
27
what is the max yield of atp obtained in cellular respiration per molecule of glucose?
30-32
28
glycolysis made 2 atp, citric acid cycle made 2 atp, so far 4 made. how have they been made
substrate level phosphorylation
29
most of the atp generated is via oxidative phosphorlyation.
1 nadh molecule makes 2.5 atp and 1fadh2 makes 1.5 atp
30
10 nadh, 2 fadh and 4 atp from glycolysis and cac
10 nadh = 25, 2 fadh = 3 + 4 = 32
31
why is there a range for atp produced per molecule of glucose
depeds on the type of cell:
32
intermediates of the cac can be used to make?
amino acids. fatty acids can be made from acetyl coa
33
what is the key regulator of cellular respiration?
phosphofructokinase
34