metabolism 3 Flashcards

1
Q

where does the citric acid cycle occur?

A

mitochondrial matrix

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2
Q

does citric cycle require oxygen?

A

no but it is considered an aerobic process because it takes place in the presence of oxygen.

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3
Q

the pyruvate enter the?

A

matrix

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4
Q

in thepresence of nad+, pyruvate

A

oxidizes to form acetyl coA and produces 1 nadh for each pryvate oxidizing = 2

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5
Q

acetyl coa enters the

A

citric acid cycle

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6
Q

how many steps in the citric acid cycle?

A

8 and has 8 enzymes

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7
Q

how many nadh co2 atp and acetyl coa before the citric acid cycle?

A

4 nadh , 2 co2, 2 atp, and 2 acetyl coA

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8
Q

what was made after the citric acid cycle?

A

1 atp in step 5, 3 adh in steps 3,4,8, 1 fadh2 in step 6 and 2 co2 in step 3 and 4

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9
Q

how many times does the citric acid cycle go around oe molecule of glucose?

A

for each molecule of glucose, the citric cycle goes around 2x. so for one molecule of glucose, 2 ATP, 6 NADH, 2 FADH2, AND 4 CO2

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10
Q

has glucose been fully oxidized by this point?

A

yes

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11
Q

after the citric acid cycle, __ molecules of NADH and ___ molecules of FADH2 have been generated.

A

6 nadh and 2 fadh2

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12
Q

these molecules are carrying ?

A

high energy electrons with potential energy

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13
Q

this stored energy is used to drive atp synthesis in the process of?

A

oxidative phosphorylation

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14
Q

what happens. next?

A

the electrons are transferred from one electron carrier to another until they combbine with o2 and h to form h20.

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15
Q

where does etc occur?

A

inner membrane of mitochondria

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16
Q

the process by which atp is made from energy released by the etc is called

A

oxidative phosphorlyation: the use of redox reaxtions in an etc to produce the energy needed to attach pi to adp to make atp.

17
Q

the enzyme that makes atp from adp and pi is called

A

atp synthase

18
Q

this reaction is endergonic, where does the cell get the energy from?

A

ion gradient of h+ that exists across the inner mitochondrial membrane

19
Q

how is the h+ gradient generated

A

by the etc

20
Q

when the electrons are transferred from one carrier to the next,

A

a small amount of energy is released and that is used to pump h+ across the membrane from the matric to the intermembrane space

21
Q

the electron carriers pick up and release protons when they pick up electrons

A

yes

22
Q

the h+ gradient that exists is called the

A

proton motive force

23
Q

after movement into the intermembrane space, there

A

is now an electrochemical difference across the inner membrane

24
Q

since h+ is an ion, it cannot diffuse across membrane on its own..

A

it passes through the channel formed by the atp synthase

25
Q

making atp is a type of work?

A

chemical work what is the energy soruce?? proton gradient formed by the etc aka pmf

26
Q

what is chemiosmosis?

A

an energy coupling mechanism that makes use of proton gradient to drive cellular work:
- mitochondria uses it to make atp
- planrs use it to transport molecules proton pump
- bacteria use it to rotate flagella

27
Q

what is the max yield of atp obtained in cellular respiration per molecule of glucose?

A

30-32

28
Q

glycolysis made 2 atp, citric acid cycle made 2 atp, so far 4 made. how have they been made

A

substrate level phosphorylation

29
Q

most of the atp generated is via oxidative phosphorlyation.

A

1 nadh molecule makes 2.5 atp and 1fadh2 makes 1.5 atp

30
Q

10 nadh, 2 fadh and 4 atp from glycolysis and cac

A

10 nadh = 25, 2 fadh = 3 + 4 = 32

31
Q

why is there a range for atp produced per molecule of glucose

A

depeds on the type of cell:

32
Q

intermediates of the cac can be used to make?

A

amino acids. fatty acids can be made from acetyl coa

33
Q

what is the key regulator of cellular respiration?

A

phosphofructokinase

34
Q
A