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Pathology Unit 5 > Metabolic: Obesity > Flashcards

Metabolic: Obesity Flashcards

1
Q

“energy expended at complete rest. lying down in the postabsorptive state”

A

BMR

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2
Q

BMR accounts for what % of TDEE?

A

60%

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3
Q

What organ is the central homeostatic controller of body weight?

A

the brain

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4
Q

What section of the brain processes external signals and manages energy balance?

A

arcuate nucleus of the hypothalamus

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5
Q

“appetite stimulating peptides”

A

orexigenic

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6
Q

“appetite inhibiting peptides”

A

anorexigenic

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7
Q

Orexigenic or anorexigenic?

ghrelin

A

orexigenic

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8
Q

Orexigenic or anorexigenic?

NPY

A

orexigenic

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9
Q

Orexigenic or anorexigenic?

POMC

A

Anorexigenic

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10
Q

Orexigenic or anorexigenic?

galanin

A

orexigenic

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11
Q

Orexigenic or anorexigenic?

insulin

A

orexigenic

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12
Q

Orexigenic or anorexigenic?

Leptin

A

anorexigenic

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13
Q

Orexigenic or anorexigenic?

GLP-1

A

Anorexigenic

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14
Q

Orexigenic or anorexigenic?

Amylin

A

anorexigenic

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15
Q

Orexigenic or anorexigenic?

CCK

A

Anorexigenic

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16
Q

Orexigenic or anorexigenic?

Thyroid hormone

A

Anorexigenic

17
Q

Orexigenic or anorexigenic?

PPAR

A

orexigenic

18
Q

Which carried a greater risk of diabetes/ HTN, heart disease….visceral or lower body fat?

A

visceral

19
Q

Name some genetic risk factors of obesity?

A

Mutations in leptin, leptin receptor, POMC

20
Q

“extreme obesity, rregular breathing, cyanosis, secondary polycythemia, RV dysfunction, persistent pulmonary HTN”

A

Pickwickian Syndrome

21
Q

Fat cells in obesity undergo…

A

Hyperplasia and hypertrophy

Pathology Unit 5 (18 decks)

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