Bone: Tumors of Bone

Question 1

Name the tumor:

benign tumor, metaphysis of long bone, whored oattern of spindle cells

Answer 1

Nonossifying fibroma

Question 2

Name the tumor:

children/adolescent, benign, fluid filled and unilocular lesion, males

Answer 2

solitary bone cyst

Question 3

Name the tumor:

children/ young adults, pain/ swelling and rapid growth with possible “blow out” rupture and hemorrhage

Answer 3

Aneurysmal bone cyst

Question 4

Name the tumor:

benign tumor of compact cortical bone, if multiple associated with gardner syndrome

Answer 4

osteoma

Question 5

Name the tumor:

benign, painful lesion pf osseous tissue (the nidus) and surrounded by a halo of reactive bone formation, diaphysis of tubular leg bones, painful at NIGHT and with ALCOHOL

pain relieved by aspirin

Answer 5

Osteoid osteoma

Question 6

Name the tumor:

uncommon, benign, large, resembles osteoid osteoma, NO NOCTURNAL PAIN, spine and long bones

Answer 6

osteoblastoma

Question 7

Name the tumor:

benign intrapsseous tumor of mature hyaline cartilage, METACARPLES and PHALANGES of the hands

Answer 7

Solitary chondroma (enchondroma)

Question 8

Name the tumor:

benign, epiphysis of long bones, males, sheets of primitive chondroblasts and primitive matrix, bone destruction with pain

Answer 8

Chondroblastoma

Question 9

Most common primary malignant bone tumor?

Answer 9

osteosarcoma

Question 10

Name the tumor:

boys, age 10-20, Rb and p53 mutations, enlarging lytic and blastic mass of disorganized bone tissue

Answer 10

Osteosarcoma

Question 11

Where does osteosarcoma usually metastasize to?

Answer 11

lungs

Question 12

What is osteosarcoma (+) for?

Answer 12

AP (+) and osteonectin (+)

Question 13

Name the tumor:

cartilagnous malignancy?

Answer 13

chondrosarcoma

Question 14

What are the common varients of chondrosarcoma?

Answer 14

1- central chondrosarcoma (most common)

2- periheral condrosarcoma

3- juxtacortical chondrosarcoma

Question 15

Name the tumor:

benign locally aggressive neoplasm characterized by the presence of osteoclastic, multinucleated giant cell

Answer 15

giant cell tumor

Question 16

T/F: giant cell tumor commonly recurrs after resection

Answer 16

true

Question 17

Name the tumor:

primitive neuroectodermal tumor of childhood, boys, Homer-Write rosettes, lytic lesions, “onion skin” periosteal reaction

Answer 17

Ewing Sarcoma

Question 18

Name the tumor:

plasma cell tumor, lytic bone lesions, cytokine release that recruitss osteclasts, amyloid deposits

Answer 18

Multiple myeloma

Question 19

Which carcinomas are known to met to bone?

Answer 19

Breast, prostate, lung, thyroid, kidney, wilms tumor

Question 20

Which mets produce dense foci?

Answer 20

prostate
breast
lung
stomach

Question 21

Which mets produce lytic lesions?

Answer 21

thyroid
GI
Kidney
Neuroblastoma