Kidney: Acute Renal Failure Flashcards
What is the hallmark of ARF?
Azotemia
What lab values indicate azotemia?
Inc BUN and Cr
Cause of prerenal azotemia?
decreased blood flow to the kidneys
BUN: Cr ratio in prerenal azotemia?
> 15
FeNa in prerenal azotemia?
<1%
What causes postrenal azotemia?
obstruction of urinary tract downstream from the kidney
BUN: Cr ratio in postrenal azotemia?
> 15 early
<15 late (due to tubular damage)
FeNa in postrenal azotemia?
2% late
“injury and necrosis of tubular epithelial cells”
Acute Tubular Necrosis
What is the MOST common cause of intrarenal acute renal failure?
Acute Tubular Necrosis
What can cause ATN?
Ischemic or nephrotoxic
What is a diagnostic finding in ATN?
Brown granular casts
BUN: Cr in ATN?
<15
FeNa found in ATN?
> 2%
What segment of tubules are particilary sensitive?
PT and TaL