Menstrual Cycle Worksheet Flashcards
What are the 4 phases of endometrial cycle?
Proliferation
Secretory
Ischemic
Menstrual
What is the endometrial cycle influenced by?
Hypothalamic-pituitary-ovarian axis feedback mechanism
Explain the hypothalamic-pituitary-ovarian axis feedback mechanism.
When the hypothalamic-pit-ovarian axis feedback mechanism functions properly, other tissues undergo predictable responses.
EX: Before ovulation, BBT is less than 37C; after ovulation (with increasing progesterone levels) BBT rises
EX2: Changes in cervix and cervical mucos follow a predictable pattern..Preovu and postov mucus is viscous so that sperm penetration is discouraged–at time of ovulation, the mucus is clear and thin [it looks, feels, and stretches like egg white–the stretchable quality is called spinnbarkeit]
EX3: Some women have localized lower abdominal pain called mittelschmerz that coincides with ovulation
What are main hormones associated with endometrial cycle?
Estrogen and progesterone
Endometrial Cycle: Proliferation phase
What happens here?
A significant rich layer of myometrium and blood vessels develops to cover the endometrial cavity
Endometrial Cycle: Proliferation phase
What does this phase correlate with? What does it depend on? Can this phase support an implanted ovum?
Correlates with: Follicular phase of OVARIAN cycle
Depends on the dominance of ESTROGEN stimulation from the ovarian follicles
This phase DOES NOT adequately support and implanted ovum
Endometrial Cycle: Secretory phase
What is this phase characterized by?
Deepening and maturing of the succulent layer of endometrium implantation
Endometrial Cycle: Secretory phase
This phase is characterized by deepening and maturing of the succulent layer of endometrium implantation.
- What does this layer do?
- What is going on with progesterone at this point?
- What if pregnancy does not occur?
- This layer WILL SUPPORT the developing zygote
- Progesterone continues to be produced by the corpus lute
- If pregnancy does not occur, the corpus luteum REGRESSES, ischemia of endometrium develops, and cyclic menstrual bleeding begins
First day of the menstrual cycle is ___. What phase is this in?
Day 1; ischemic phase
What happens in the ischemic phase of the endometrial cycle?
Shedding of functional 2/3 of endometrium
What are the 3 phases of the ovarian cycle?
Follicular phase (pre-ovulatory)
Ovulation
Luteal (post-ov)
T/F: Blood levels of the ovarian hormones (estrogen and progesterone) increase toward the end of the normal menstrual cycle.
FALSE–They decline!!!
The low blood levels of hormones at the end of a normal menstrual cycles triggers the _____ to begin a new ovarian cycle by secreting _____
Hypothalamus to begin a new ovarian cycle by secreting gonadotropin-releasing hormone (GnRH)
GnRH stimulates the _______ to secrete _______ and _____. What is the target organ of these hormones?
GnRH stimulates the ANTERIOR PITUITARY to secrete follicle stimulating hormone (FSH) and luteinizing hormone (LH)
The target organ of these hormones is the OVARY
What is dominant in the follicular phase: FSH or LH? Why?
FSH…it stimulates the development of ovarian griffin follicles
One of these follicles will develop into a mature ova and a surge of LH causes the mature ova to be released from the ovary
What does a surge of LH cause?
The mature ova to be released from the ovary
The developing follicles produce ____ and ____ in large amounts. What do these hormones prepare?
Estrogen and progesterone
These hormones prepare the endometrial lining of the uterus for implantation of a zygote!
When does ovulation occur? What happens when these hormones peak?
After a marked surge of LH and a smaller peak of estrogen 14 days (+/- 2 days) before the next menstrual flow
When the hormones LH and estrogen peak, ovulation occurs within 24-36 hours
Clinical signs of ovulation: What happens in the body basal temp (BBT)?
Sharp increase in body temp
Clinical signs of ovulation: What happens to the vaginal mucus?
It becomes thin and stretchable (spinnbarkeit)