Menopause Flashcards

1
Q

When is the avg age of menopause?

A

~51 years

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2
Q

What is considered as being early menopause?

A

<45 y.o

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3
Q

Premature menopause?

A

<40 y.o

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4
Q

Age of late menopause?

A

> 54 y.o

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5
Q

How many ova does one born with?

A

1 million!!

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6
Q

Efx of estrogen?

A
  • IIary sexual characteristics

- –hair/ body shape/ fat distribution/ bone GROWTH/ endometrium proliferation

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7
Q

In what situations does FSH and LH raise?

A
  1. prior to OVULATION
  2. with STOPPING combined OCP or depoprovera
  3. Raised with breastfeeding or SSRI use
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8
Q

Does a single raised level of FSH and LH suggest menopause?

A

NO

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9
Q

How is FSH and LH released usually?

A
  • pulsatile fashion
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10
Q

What are the physical symptoms of menopause?

A
Hot flushes
Night sweats
Palpitations
Insomnia
Joint aches
Headaches
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11
Q

How long do hot flushes last?

A
  • 3-5mins

- ~2 years (10% for 15 years!!)

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12
Q

Psychological problems with menopause?

A
  • mood swings/ irritable/ anxiety/ forgertfulness
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13
Q

What sexual changes occurs with menopause?

A
  • vaginal DRYNESS

- libido

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14
Q

What other symptoms may arise in menopause?

A
  • UTIs/ dysuria/incontinence/freq.
  • dry hair and skin
  • atrophy of breast and genitals
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15
Q

What bleeding disorders occur with menopause?

A
  • irregular periods
  • intra-menstrual bleeding
  • post-menopausal bleeding
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16
Q

How to manage menorrhagia?

A
  • mefenamic acid
  • tranexamic acid
  • progesterones
  • Intra-uterine sys
  • endometrial ABLATION
  • hysterectomy
17
Q

How are the short-term symptoms managed according to the NICE guidelines?

A
  • consider HRT to alleviate mood:
    1. estrogen and progesterone pills (those with UTERUS)
    2. estrogen only pills (those w.o uterus)
  • do NOT routinely offer SSRIs to treat vasomotor symptoms
  • testosterone supplements for those with LOW sexual drive
18
Q

How to manage urogenital atrophy?

A
  • vaginal estrogen
19
Q

When is HRT contraindicated?

A
  • breast cancer
  • undx abnormal vaginal bleeding
  • endometrial cancer
  • pregnancy
  • thrombo-emoblic d.o
  • recent MI
  • liver disease with abnormal LFT
  • porphyria cutanea tarda