meningitis Flashcards

1
Q

define meningitis?

A

inflammation of the leptomeninges

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2
Q

what are the leptomeninges?

A

arachnoid and pia

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3
Q

define meningoencephalitis

A

inflammation of the leptomeninges + underlying brain

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4
Q

etymology of meninges?

A

mening (greek) = membrane

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5
Q

etymology of leptomeninges?

A

leptos = thin

mening (greek) = membrane

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6
Q

prevalence per 100,000?

A

2-5/100,000

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7
Q

most common cause of meningitis?

A

infection

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8
Q

risk factors for meningitis?

A

Immunocompromised
Not vaccinated
Crowded environments

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9
Q

order of meninges

A

DAP

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10
Q

why would an old person or a person with HIV be at risk of meningitis?

A

immunocompromised

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11
Q

what type of rash could a pt with meningitis have?

how do you test if it is said rash?

result of said test?

A

non-blanching rash

press glass against it,

will not disappear

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12
Q

cause of meningococcus meningitis?

A

Neisseria meningitidis

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13
Q

most common bacterial cause of meningitis in neonates?

A

Group B streptococcus

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14
Q

most common bacterial cause of meningitis? (regardless of age)

A

S. Pneumonia

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15
Q

most common viral cause of meningitis?

A

enteroviruses

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16
Q

which is more common cause of meningitis:

HSV-2 meningitis or HSV-1 meningitis

A

HSV-2 meningitis

17
Q

HSV-2 meningitis is what type of virus?

  • basically what does it stand for?
A

herpes simples virus

18
Q

coxsackie & echovirus come under what group of viruses?

A

enteroviruses

19
Q

of bacteria, viruses and fungi which is rarest cause of meningitis?

20
Q

of bacteria and viral cause of meningitis,

which is more common?

21
Q

of bacteria and viral cause of meningitis,

which is more lethal?

22
Q

of bacteria and viral cause of meningitis,

which is usually self-limiting?

23
Q

a non blanching rash is associated with which type of meningitis?

A

meningococcal disease

24
Q

meningism is a clinical syndrome.

what is classic triad of symptoms?

A

Headache
Photophobia
Neck Stiffness

25
aside from meningism what other symptoms can occur?
Confusion Fever N&V Seizures
26
what is Kernig's sign?
hip flexed and knee at 90°, | extension of the knee causes pain
27
what is brudzinski sign?
severe neck stiffness causes hips and knees to flex when neck is flexed.
28
pt confirmed with infective meningitis: which drug is given prophylactically to contacts?
ciprofloxacin.
29
pt comes to hospital with meningitis. what drug is given immediately before Ix are done? what is route?
IV ceftriaxone
30
what Ix are done for pt with suspected meningitis? -7 why do you do each/ what result would indicate meningitis?
FBC - leukocytosis CRP – raised Coagulation screen – required prior to LP Blood glucose – need to compare to CSF glucose Blood culture - +ve if bacterial infection Whole-blood PCR - for N meningitidis LP & CSF analysis
31
pt with suspected meningitis. two reasons why LP might be CI?
increased ICP meningococcal septicaemia
32
most common complication of meningitis?
Sensorineural hearing loss
33
severe complication you must be wary of with meningitis and really any infection?
sepsis
34
mortality rate of Meningococcal meningitis in adults?
10%
35
mortality rate of pneumococcal meningitis?
22%
36
you are a GP. pt comes and you suspect meningococcal meningitis due to a particular type of rash and some other symptoms. what type of rash is it? what must you as GP give immediately? where must you send pt now ASAP?
non-blanching rash Benzylpenicillin (IM/IV) hospital
37
what blood test must you do before a LP?
coagulation screen