case 6

Question 1

pick’s disease is also known as?

Answer 1

frontotemporal dementia

Question 2

which lobes of brain are effected by pick’s disease?

-2

Answer 2

frontal and temporal

Question 3

key feature of pick’s disease?

Answer 3

personality changes

Question 4

which memory type is preserved in amnesia?

which two memory types are effected in amnesia?

Answer 4

procedural

episodic and semantic

Question 5

valleys in brain are called what?

Answer 5

sulci

Question 6

which sulcus separates the frontal and temporal lobe of brain?
- 2 names

Answer 6

lateral sulcus or

sylvian fissure

Question 7

ACA supplies what parts of the brain?

Answer 7

front of the brain

Question 8

MCA supplies what parts of the brain?

Answer 8

sides of brain

Question 9

PCA supplies what parts of the brain?

Answer 9

back of brain

Question 10

flow of CSF

Answer 10

LV –> via interventricular foramen to 3rd ventricle –> via cerebral aqueduct to 4th ventricle –> subarachnoid space –> reabsorbed by arachnoid villi

Question 11

where is CSF made mainly?

Answer 11

lateral ventricles

Question 12

what brain structure encodes new memories?

Answer 12

hippocampus

Question 13

what brain structure is involved in aggression, rage and PTSD?

Answer 13

amygdala

Question 14

5 structures of the limbic system?

Answer 14

amygdala
hippocampus
thalamus
hypothalamus
cingulate gyrus.

Question 15

nuclei are grey or white matter?

Answer 15

grey matter

Question 16

tracts are grey or white matter?

Answer 16

white matter

Question 17

a nuclei in the brain is literally what?

Answer 17

cluster of cell bodies

Question 18

which cells do myelination in the brain?

Answer 18

ogligodendrocytes

Question 19

which cells do myelination in the PNS?

Answer 19

schwann cells

Question 20

which cells are involved in BBB, synapse foramtion and neurogenesis?

Answer 20

astrocytes

Question 21

abnormal increase in number of astrocytes is called what?

Answer 21

astrogliosis

Question 22

which cells are the immune system of the brain?

Answer 22

microglia

Question 23

which brain cell is star shaped?

Answer 23

astrocytes

Question 24

which brain cell is located near the synapse and regulates calcium levels?

Answer 24

astrocytes

Question 25

which cells in the brain are ciliated and cuboidal in shape?

Answer 25

ependymal cells

Question 26

which cells in the brain make CSF?

Answer 26

ependymal cells

Question 27

major excitatory neurotransmitter in the CNS?

Answer 27

glutamate

Question 28

major inhibitory neurotransmitter in the CNS?

Answer 28

GABA

Question 29

which neurotransmitters are the monoamines? | -3

Answer 29

Da 5HT Noradrenaline

Question 30

what are the 4 long term memory categories?

Answer 30

semantic episodic procedural classically conditioned

Question 31

what value is Miller's magic number?

Answer 31

7

Question 32

what is the central executive responsible for? where is the central executive located in the brain?

Answer 32

working memory pre-frontal cortex

Question 33

the phonological loop is comprised of what two brain areas?

Answer 33

broca's | wernicke's

Question 34

what links working memory to long-term memory?

Answer 34

episodic buffer

Question 35

what is Ribot's Law?

Answer 35

damage typically spares remote memory and impairs more recent memory

Question 36

damage to frontal lobe leads to exaugurated results in what test?

Answer 36

stoop test

Question 37

which part of the brain changes with age first?

Answer 37

frontal lobe

Question 38

normal MOCA score?

Answer 38

>26

Question 39

usual MOCA score for someone with mild cognitive impairment?

Answer 39

22

Question 40

usual MOCA score for someone with Alzheimer's?

Answer 40

16

Question 41

define longitudinal study?

Answer 41

look at one group throughout their life

Question 42

define cross-sectional study?

Answer 42

look at different groups at different ages at one point in time.

Question 43

which brain lobe changes first with old age?

Answer 43

frontal lobe

Question 44

what happens to brain processing speed with age?

Answer 44

slows down

Question 45

which is the only memory type that improves with age?

Answer 45

semantic

Question 46

which is the only brain region that increases with age?

Answer 46

ventricles

Question 47

which brain region shrinks most rapidly with age?

Answer 47

frontal lobe

Question 48

what happens to hippocampus size with age?

Answer 48

decreases

Question 49

which neurotransmitter is involved in memory making?

Answer 49

AcH

Question 50

define Alzheimer's dementia?

Answer 50

impaired memory + one other cognitive ability impaired (e.g. language, judgement, perception, planning)

Question 51

which gene if mutated is a risk factor for dementia? what chromosome is it on?

Answer 51

APOE4 chromosome 21

Question 52

which proteins build in the brains of Alzheimer's patients?

Answer 52

B amyloid peptide Tau protein

Question 53

which type of memory is affect most severely in Alzheimer's?

Answer 53

episodic

Question 54

which proteins build in the brains of Alzheimer's patients? which of these proteins build inside the cell and which outside the cells?

Answer 54

B amyloid peptide - extracellularly Tau protein - intracellularly

Question 55

dementia affects what part of the brain?

Answer 55

medial temporal lobe

Question 56

hippocampus is where in the brain?

Answer 56

medial temporal lobe

Question 57

episodic memory if effected first with Alzheimer's, as the Alzheimer's progresses can other memory types be effected also?

Answer 57

yes