BZD overdose benzodiazepines

Question 1

BZD has what effect on CNS?

Answer 1

depresses it

Question 2

uses for BZD

-4

Answer 2

insomnia, seizure, anxiety, rapid transquilisation

Question 3

which BZD is good in the acutely agitated?

and why?

Answer 3

lorazepam

quick effect

Question 4

BZD has what effect on what neurotransmitter?

is this neurotransmitter excitatory or inhibitory?

Answer 4

↑GABA

inhibitory

Question 5

most lethal complication of BZD overdose?

Answer 5

respiratory depression

Question 6

what is classical triad of symptoms from BZD overdose?

Answer 6

respiratory depression + ataxia + low consciousness

Question 7

main sign on doing news chart?

Answer 7

low O2

Question 8

ABG result on pt with BZD overdose?

Answer 8

resp acidosis

Question 9

GCS score is high or low on BZD overdose?

Answer 9

GCS low

Question 10

1st line Mx for BZD overdose?

Answer 10

IV fluids

Question 11

2nd Line Mx for BZD overdose?

is this option regularly done?

Answer 11

FLUMAZENIL

no, rare to do

Question 12

drug to treat BZD overdose?

Answer 12

Flumazenil

Question 13

moa of flumazenil?

Answer 13

BZD antagonist

Question 14

major SE of flumazenil?

Answer 14

seizures

Question 15

pt has severe resp depression.

What is Mx?

Answer 15

mechanical ventilation

Question 16

why are older people at high risk of any overdose

Answer 16

Reduced drug clearance with age

Question 17

BZD overdose,

what happens to pupil size?

Answer 17

stay same, no effect

Question 18

opiate overdose,

what happens to pupil size?

Answer 18

constricts

Question 19

Amphetamines, cocaine, LSD overdose,

what happens to pupil size?

Answer 19

dilates

Question 20

BZD overdose often causes death.

true or false?

Answer 20

false