Meninges, Ventricles, Vasculature Flashcards
Dura Mater
The strong outer “envelope” between the skull and the arachnoid layer
forms Dural Reflections and Dural Sinuses
has pain receptors
Dural Reflections
Folds in the Dura that partially separate different intracranial compartments
Falx Cerebri
fold that separates the two cerebral hemisphere
Falx Cerebelli
partially separates the cerebelli
Tentorium Cerebelli
fold that separates the cerebellum and cerebrum
- defines the supratentorial (contains cerebrum) and infratentorial compartment (cerebellum and brainstem)
Diaphragma Sellae
reflection that cover the pitu fossa. The infundibulum goes through a small hole here
Tentorial Notch
the space in the tentorium through which the brain stem passes
Dural Sinuses
where the cerebral veins empty - Superior and Inferior Sagittal sinus - Right and Left Transverse sinus - Straight sinus these drain into the confluence of sinuses - sigmoid sinus
Arachnoid
part of leptomeninges
attached to the inside of the dura
does not line the brain down into its sulci
CSF flows under this membrane
Arachnoid Trabecula
strands of connective tissue that loosely connect the arachnoid and pia mater
CSF contained here
Arachnoid Mater-cisterns
openings in subarachnoid space of the brain created by a separation of the arachnoid and pia mater
filled with CSF
- Cerebellomedullary cistern
- Pontine cistern
Arachnoid Villi
small protrusions of the arachnoid that reach into the dural sinus
where CSF moves from subarachnoid space –> through arachnoid villi –> dural sinus
Arachnoid Granulations
collection of arachnoid villi
form pacchionian bodies with age
Epidural Space
between dura and skull
may be opened up by blood from a ruptured meningeal artery/torn dural venous sinus
spinal meninges do have a normal epidural space
Subdural Space
may be opened up by blood from a vein that tears as it crosses the arachnoid to enter a dural sinus
Ventricles (flow of CSF)
Lateral ventricles –> foramen of Monro –> 3rd ventricle –> cerebral aqueduct –> 4th ventricle –> foramen of Magendie and foramen of Luschka –> Cistern Magna and Pontine Cistern –> spinal cord central canal –> tentorial notch –> arachnoid villi –> superior sagittal sinus
Choroid Plexus
modified capillaries that synthesise CSF (only in ventricles, not foramens)
Anterior Cerebral Artery
provides blood to the medial surface of each cerebral hemisphere
Middle Cerebral Artery
provides blood to the lateral surface of each cerebral hemisphere
Posterior Cerebral Artery
provides blood to the medial and lateral surface of each occipital lobe
Blood Brain Barrier (function)
- protects brain from ‘foreign substances’ that can infect or damage the brain
- protects the brain from systemic hormones and neurotransmitters
- maintains a constant environment
Endothelial cells
cells that have tight junctions between them that restrict the diffusion of microscopic objects and large/hydrophilic molecules into CSF
allows diffusion of hydrophobic molecules eg O2
Astrocytes
cell projections called astrocytic end feet surround the endothelial cells of the BBB
provides biochemical support
Arachnoid Mater
tight junctions that keep substances from entering the brain
Subfornical Organ
small nodule in the anterior, superior corner of the third ventricle
controls fluid balance and drinking behavior